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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sortilin 1
Summary
- Gene Symbol
-
- SORT1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cleavage on pair of basic residues
- Developmental protein
- Differentiation
- Direct protein sequencing
- Disulfide bond
- Endocytosis
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Lysosome
- Nucleus
- Osteogenesis
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| Q99523 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| clathrin-coated vesicle | ||
| endoplasmic reticulum membrane | ||
| plasma membrane | ||
| cell surface | ||
| Golgi cisterna membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| retromer complex binding | ||
| neurotensin receptor activity, non-G protein-coupled | ||
| enzyme binding | ||
| nerve growth factor receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- sortilin
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Sortilin, C-terminal |
| Sortilin, N-terminal |
| VPS10 |
| WD40/YVTN repeat-like-containing domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:7693 | abdominal aortic aneurysm |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 103224291 | CHLSB08608 | |||
| 103674994 | URSMA12385 | |||
| 103747872 | NANGA11628 | |||
| 104655888 | RHIRO38512 | |||
| 105479283 | MACNE25508 | |||
| 105530956 | MANLE38316 | |||
| 105594332 | CERAT38622 | |||
| 105727857 | AOTNA31169 | |||
| 105813755 | PROCO25192 | |||
| 105997474 | DIPOR18233 |
