Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
sodium voltage-gated channel alpha subunit 5
Summary
- Gene Symbol
-
- SCN5A
- Organism
- Homo sapiens (human)
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane depolarization during bundle of His cell action potential | ||
| AV node cell to bundle of His cell communication | ||
| regulation of heart rate by cardiac conduction | ||
| membrane depolarization during atrial cardiac muscle cell action potential | ||
| regulation of sodium ion transmembrane transport |
GO Hierarchy
- membrane depolarization during AV node cell action potential
- membrane depolarization during SA node cell action potential
- membrane depolarization during Purkinje myocyte cell action potential
- membrane depolarization during bundle of His cell action potential
- membrane depolarization during atrial cardiac muscle cell action potential
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of biological quality [inference]
regulation of membrane potential [inference]
membrane depolarization
membrane depolarization during action potential
membrane depolarization during cardiac muscle cell action potential
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel complex | ||
| voltage-gated sodium channel complex | ||
| voltage-gated sodium channel complex | ||
| nucleoplasm | ||
| nucleolus |
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel activity | ||
| voltage-gated sodium channel activity | ||
| voltage-gated sodium channel activity | ||
| protein binding | ||
| calmodulin binding |
GO Hierarchy
- voltage-gated sodium channel activity involved in AV node cell action potential
- voltage-gated sodium channel activity involved in bundle of His cell action potential
- voltage-gated sodium channel activity involved in Purkinje myocyte action potential
- voltage-gated sodium channel activity involved in SA node cell action potential
- voltage-gated sodium channel activity involved in AV node cell action potential
- voltage-gated sodium channel activity involved in bundle of His cell action potential
- voltage-gated sodium channel activity involved in Purkinje myocyte action potential
- voltage-gated sodium channel activity involved in SA node cell action potential
- voltage-gated sodium channel activity involved in AV node cell action potential
- voltage-gated sodium channel activity involved in bundle of His cell action potential
- voltage-gated sodium channel activity involved in Purkinje myocyte action potential
- voltage-gated sodium channel activity involved in SA node cell action potential
- voltage-gated sodium channel activity involved in AV node cell action potential
- voltage-gated sodium channel activity involved in bundle of His cell action potential
- voltage-gated sodium channel activity involved in Purkinje myocyte action potential
- voltage-gated sodium channel activity involved in SA node cell action potential
- voltage-gated sodium channel activity involved in AV node cell action potential
- voltage-gated sodium channel activity involved in bundle of His cell action potential
- voltage-gated sodium channel activity involved in Purkinje myocyte action potential
- voltage-gated sodium channel activity involved in SA node cell action potential
- voltage-gated sodium channel activity involved in AV node cell action potential
- voltage-gated sodium channel activity involved in bundle of His cell action potential
- voltage-gated sodium channel activity involved in Purkinje myocyte action potential
- voltage-gated sodium channel activity involved in SA node cell action potential
molecular function
transporter activity [inference]
transmembrane transporter activity [inference]
monoatomic ion transmembrane transporter activity [inference]
monoatomic ion channel activity [inference]
monoatomic cation channel activity [inference]
sodium channel activity [inference]
voltage-gated sodium channel activity
voltage-gated sodium channel activity involved in cardiac muscle cell action potential
monoatomic cation transmembrane transporter activity [inference]
monoatomic cation channel activity [inference]
sodium channel activity [inference]
voltage-gated sodium channel activity
voltage-gated sodium channel activity involved in cardiac muscle cell action potential
metal ion transmembrane transporter activity [inference]
sodium ion transmembrane transporter activity [inference]
sodium channel activity [inference]
voltage-gated sodium channel activity
voltage-gated sodium channel activity involved in cardiac muscle cell action potential
inorganic molecular entity transmembrane transporter activity [inference]
inorganic cation transmembrane transporter activity [inference]
metal ion transmembrane transporter activity [inference]
sodium ion transmembrane transporter activity [inference]
sodium channel activity [inference]
voltage-gated sodium channel activity
voltage-gated sodium channel activity involved in cardiac muscle cell action potential
passive transmembrane transporter activity [inference]
channel activity [inference]
monoatomic ion channel activity [inference]
monoatomic cation channel activity [inference]
sodium channel activity [inference]
voltage-gated sodium channel activity
voltage-gated sodium channel activity involved in cardiac muscle cell action potential
salt transmembrane transporter activity [inference]
sodium ion transmembrane transporter activity [inference]
sodium channel activity [inference]
voltage-gated sodium channel activity
voltage-gated sodium channel activity involved in cardiac muscle cell action potential
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050650 | familial atrial fibrillation | |
| DOID:0110218 | Brugada syndrome 1 | |
| DOID:0110433 | dilated cardiomyopathy 1E | |
| DOID:0110646 | long QT syndrome 3 | |
| DOID:0111074 | progressive familial heart block type IA | |
| DOID:13884 | sick sinus syndrome | |
| DOID:2843 | long QT syndrome | |
| DOID:9007 | sudden infant death syndrome |
