succinate dehydrogenase complex subunit D

Summary
Gene Symbol
  • SDHD
Aliases
  • cybS
  • small subunit of cytochrome b
Organism
Homo sapiens (human)
External Links
NCBI Gene
6392
HGNC
10683
KEGG Gene ID
hsa:6392
PubChem
6392
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Disease variant
  • Electron transport
  • Heme
  • Mitochondrion inner membrane
  • Primary mitochondrial disease
  • Reference proteome
  • Signal
  • Transit peptide
  • Transmembrane helix
  • Tricarboxylic acid cycle
Proteins
Displaying all 3 entries
UniProt Protein Name
O14521
  • CII-4
  • Malate dehydrogenase [quinone] cytochrome b small subunit
  • QPs3
  • Succinate dehydrogenase complex subunit D
  • Succinate-ubiquinone oxidoreductase cytochrome b small subunit
  • Succinate-ubiquinone reductase membrane anchor subunit
A0A0S2Z4H7
A0A0S2Z4J3
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
Human Protein Atlas
ENSG00000204370

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

KEGG BRITE Database
Orthology
K00237
Name
succinate dehydrogenase (ubiquinone) membrane anchor subunit
References
Disease
Disease Ontology
Displaying entries 1 - 10 of 249 in total
DO ID Disease Name Source
DOID:10952 nephritis
DOID:0050387 nonpapillary renal cell carcinoma
DOID:0050426 Stevens-Johnson syndrome
DOID:0050428 nonepidermolytic palmoplantar keratoderma
DOID:0050430 multiple endocrine neoplasia type 2A
DOID:0050486 exanthem
DOID:0050572 cone-rod dystrophy
DOID:0050657 Bannayan-Riley-Ruvalcaba syndrome
DOID:0050700 cardiomyopathy
DOID:0050757 deafness-dystonia-optic neuronopathy syndrome
The Human Phenotype Ontology
Displaying entries 1 - 10 of 200 in total
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0000007 Autosomal recessive inheritance
HP:0000036 Abnormal penis morphology
HP:0000076 Vesicoureteral reflux
HP:0000077 Abnormality of the kidney
HP:0000093 Proteinuria
HP:0000096 Glomerular sclerosis
HP:0000130 Abnormality of the uterus
HP:0000158 Macroglossia
HP:0000218 High palate
Displaying all 9 entries
Disease ID Disease Name
ORPHA:276621
  • sporadic pheochromocytoma/secreting paraganglioma
OMIM:606864
  • Carney-Stratakis syndrome
ORPHA:201
  • Cowden disease
ORPHA:3208
  • mitochondrial complex II deficiency, nuclear type 1
ORPHA:97286
  • Carney-Stratakis syndrome
OMIM:168000
  • paragangliomas 1
OMIM:619167
  • mitochondrial complex 2 deficiency, nuclear type 3
ORPHA:29072
  • hereditary pheochromocytoma-paraganglioma
ORPHA:100093
  • carcinoid syndrome

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Last updated: August 19, 2024