succinate dehydrogenase complex subunit D
| UniProt | Protein Name |
|---|---|
| O14521 |
|
| A0A0S2Z4H7 |
|
| A0A0S2Z4J3 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrial electron transport, succinate to ubiquinone | ||
| proton motive force-driven mitochondrial ATP synthesis | ||
| regulation of catecholamine secretion | ||
| cellular response to hypoxia |
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrion | ||
| mitochondrial envelope | ||
| mitochondrial inner membrane | ||
| mitochondrial inner membrane | ||
| mitochondrial inner membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| succinate dehydrogenase (ubiquinone) activity | ||
| electron transfer activity | ||
| heme binding | ||
| heme binding |
| InterPro |
|---|
| Fumarate reductase/succinate dehydrogenase, transmembrane subunit |
| Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050773 | paraganglioma | |
| DOID:0060537 | mitochondrial complex II deficiency | |
| DOID:0080533 | Carney-Stratakis syndrome |
| HPO ID | HPO Term |
|---|---|
| HP:0100031 | Neoplasm of the thyroid gland |
| HP:0100543 | Cognitive impairment |
| HP:0100570 | Carcinoid tumor |
| HP:0100579 | Mucosal telangiectasiae |
| HP:0100635 | Carotid paraganglioma |
| HP:0100723 | Gastrointestinal stroma tumor |
| HP:0100749 | Chest pain |
| HP:0100780 | Conjunctival hamartoma |
| HP:0200034 | Papule |
| HP:0200063 | Colorectal polyposis |
| Disease ID | Disease Name |
|---|---|
| ORPHA:201 |
|
| OMIM:606864 |
|
| ORPHA:276621 |
|
| OMIM:168000 |
|
| OMIM:619167 |
|
| ORPHA:3208 |
|
| ORPHA:29072 |
|
| ORPHA:100093 |
|
| ORPHA:97286 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100937193 | PONAB03884 | ||
| 100974019 | PANPA07934 | ||
| 100992849 | PANPA07934 | ||
| 101002161 | PAPAN06029 | ||
| 101011036 | PAPAN06029 | ||
| 101095280 | FELCA25132 | ||
| 101333834 | TURTR14968 | ||
| 101334845 | TURTR14968 | ||
| 101562257 | OCTDE20385 | ||
| 101593300 | OCTDE24962 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: December 8, 2025