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solute carrier family 5 (choline transporter), member 7

Summary

Gene Symbol

Slc5a7

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

63993

PubChem

63993

Alliance of Genome Resources

MGI:1927126

Annotation

Keyword

Cell membrane
Cell projection
Cytoplasmic vesicle
Endosome
Glycoprotein
Neurotransmitter biosynthesis
Phosphoprotein
Reference proteome
Sodium transport
Symport
Synapse
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BGY9	Hemicholinium-3-sensitive choline transporter Solute carrier family 5 member 7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
transmembrane transport	IEA
synaptic transmission, cholinergic	IBA IMP	15173594 16162937
acetylcholine biosynthetic process	IBA IDA IMP ISO	11709061 15173594
neuromuscular synaptic transmission	IBA IMP	15173594
in utero embryonic development	IMP	27996060

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine biosynthetic process

organonitrogen compound biosynthetic process [inference]

acetylcholine biosynthetic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

acetate ester biosynthetic process [inference]

acetylcholine biosynthetic process

organonitrogen compound biosynthetic process [inference]

acetylcholine biosynthetic process

organic substance metabolic process [inference]

acetate ester metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine biosynthetic process

acetate ester biosynthetic process [inference]

acetylcholine biosynthetic process

organonitrogen compound metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine biosynthetic process

organonitrogen compound biosynthetic process [inference]

acetylcholine biosynthetic process

organic substance biosynthetic process [inference]

acetate ester biosynthetic process [inference]

acetylcholine biosynthetic process

organonitrogen compound biosynthetic process [inference]

acetylcholine biosynthetic process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

transmembrane transport

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

transmembrane transport

organic substance transport [inference]

organic cation transport [inference]

choline transport

quaternary ammonium group transport [inference]

choline transport

nitrogen compound transport [inference]

quaternary ammonium group transport [inference]

choline transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
apical plasma membrane	ISO
axon	IBA IEA ISO
synaptic vesicle	ISO
dendrite	IBA ISO
synapse	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

early endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft

cell junction [inference]

synapse

neuromuscular junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

cell body [inference]

neuronal cell body

Displaying **all 4** entries
GO Term	Evidence Code	PMID
choline binding	IDA	17196556
choline:sodium symporter activity	IBA ISO ISS
choline transmembrane transporter activity	IDA IMP ISO	11709061 15173594 17196556
protein binding	IPI	17709753

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

choline:sodium symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

choline:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

choline:sodium symporter activity

organic cation transmembrane transporter activity [inference]

quaternary ammonium group transmembrane transporter activity [inference]

choline transmembrane transporter activity

choline:sodium symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

choline:sodium symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

choline:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

choline:sodium symporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

choline:sodium symporter activity

choline transmembrane transporter activity

choline:sodium symporter activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

choline binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0110661	congenital myasthenic syndrome 20	Alliance of Genome Resources
DOID:0111199	autosomal dominant distal hereditary motor neuronopathy 7	Alliance of Genome Resources
DOID:1470	major depressive disorder	Alliance of Genome Resources
DOID:1596	depressive disorder	Alliance of Genome Resources
DOID:2841	asthma	Alliance of Genome Resources