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Guidelines

MIRAGE

myosin IG

Summary

Gene Symbol

MYO1G

Organism

Homo sapiens (human)

External Links

NCBI Gene

64005

PubChem

64005

Alliance of Genome Resources

HGNC:13880

JoGo

MYO1G

TogoVar

MYO1G

Annotation

Keyword

ATP-binding
Acetylation
Actin-binding
Adaptive immunity
Alternative splicing
Calmodulin-binding
Cell membrane
Cell projection
Direct protein sequencing
Lipid-binding
Myosin
Proteomics identification
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
B0I1T2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
T cell mediated immunity	ISS
exocytosis	IEA
endocytosis	IBA
actin filament organization	IBA
actin filament-based movement	IBA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

leukocyte mediated immunity [inference]

lymphocyte mediated immunity [inference]

T cell mediated immunity

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

T cell migration

T cell meandering migration

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

vesicle-mediated transport [inference]

actin filament-based process [inference]

actin filament-based movement

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

T cell migration

T cell meandering migration

cell gliding

cellular component organization or biogenesis [inference]

cellular component organization [inference]

supramolecular fiber organization [inference]

actin filament organization

export from cell [inference]

secretion by cell [inference]

exocytosis

response to stimulus [inference]

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

secretion [inference]

secretion by cell [inference]

exocytosis

import into cell [inference]

endocytosis

export from cell [inference]

secretion by cell [inference]

exocytosis

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
phagocytic cup	ISS
nucleoplasm	IDA
cytoplasm	IBA
plasma membrane	IDA	19968988
plasma membrane	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

myosin complex

cellular anatomical entity [inference]

plasma membrane

leading edge membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

actin-based cell projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
microfilament motor activity	IBA
calmodulin binding	IEA
ATP binding	IEA
phosphatidylinositol-4,5-bisphosphate binding	ISS
phosphatidylinositol-3,4,5-trisphosphate binding	ISS

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microfilament motor activity

binding [inference]

protein binding [inference]

calmodulin binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol-3,4,5-trisphosphate binding

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

phosphatidylinositol-3,4-bisphosphate binding

protein-containing complex binding [inference]

actin filament binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microfilament motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

myosin I

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
actin binding
actin filament binding
actin filament organization
cytoskeletal motor activity
nucleotide binding
vesicle transport along actin filament

Displaying **all 5** entries
InterPro
Class I myosin tail homology domain
IQ motif, EF-hand binding site
Kinesin motor domain superfamily
Myosin head, motor domain
P-loop containing nucleoside triphosphate hydrolase

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Last updated: December 8, 2025