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neuromedin U receptor 2

Summary

Gene Symbol

Nmur2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

64042

PubChem

64042

Alliance of Genome Resources

RGD:621155

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9ESQ4	G-protein coupled receptor TGR-1 G-protein-coupled receptor FM-4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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GO Term	Evidence Code	PMID
regulation of sensory perception of pain	IDA	12890516
arachidonic acid secretion	IEA ISO
neuropeptide signaling pathway	IBA IEA ISO
chloride transmembrane transport	IEA
response to pain	IEA ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

multicellular organismal process [inference]

behavior [inference]

grooming behavior

feeding behavior [inference]

eating behavior [inference]

reduction of food intake in response to dietary excess

multicellular organismal response to stress [inference]

response to pain

response to stimulus [inference]

response to stress [inference]

multicellular organismal response to stress [inference]

response to pain

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

secretion [inference]

icosanoid secretion [inference]

arachidonic acid secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

organic substance transport [inference]

lipid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

icosanoid transport [inference]

icosanoid secretion [inference]

arachidonic acid secretion

arachidonate transport [inference]

arachidonic acid secretion

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

icosanoid transport [inference]

icosanoid secretion [inference]

arachidonic acid secretion

arachidonate transport [inference]

arachidonic acid secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

regulation of sensory perception [inference]

regulation of sensory perception of pain

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	ISO
plasma membrane	IBA IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
neuromedin U receptor activity	IEA ISO
neuropeptide receptor activity	IBA IDA ISO	10894543
intracellular calcium activated chloride channel activity	IEA ISO
neuromedin U binding	IEA ISO
GTP binding	IEA ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

salt transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

binding [inference]

amide binding [inference]

peptide binding [inference]

neuropeptide binding [inference]

neuromedin U binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuromedin U receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuromedin U receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Neuromedin U receptor

Functional Category

E: Amino acid transport and metabolism
K: Transcription
L: Replication, recombination and repair
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
neuromedin U receptor activity
neuropeptide receptor activity
neuropeptide signaling pathway

Displaying **all 5** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Neuromedin U receptor, type 2
Neuromedin U receptor
Neuromedin-U receptor 2, C-terminal domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9970	obesity	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of **107** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	100498226		Xenbase:XB-GENE-6046084
Meleagris gallopavo	100546265			MELGA04181
Nomascus leucogenys	100604277			NOMLE24941
Loxodonta africana	100672000			LOXAF20198
Cavia porcellus	100715572	10141_0:00105b
Cricetulus griseus	100758157	10029_0:004429
Capra hircus	100860847			CAPHI27136
Otolemur garnettii	100961368			OTOGA18343
Pan paniscus	100986744			PANPA32989
Papio anubis	100999693			PAPAN32546