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golgi phosphoprotein 3

Summary

Gene Symbol

GOLPH3

Aliases

GOPP1
GPP34
MIDAS
Vps74
coat-protein
golgi peripheral membrane protein 1, 34 kDa
golgi protein
golgi-associated protein

Organism

Homo sapiens (human)

External Links

NCBI Gene

64083

HGNC

15452

KEGG Gene ID

hsa:64083

PubChem

64083

Alliance of Genome Resources

HGNC:15452

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
Endosome
Golgi apparatus
Lipid-binding
Mitochondrion
Phosphoprotein
Protein transport
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9H4A6	Coat protein GPP34 Mitochondrial DNA absence factor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
protein targeting to Golgi apparatus	IMP	34473204
negative regulation of apoptotic process	IMP	24485452
cell migration	IMP	23500462
asymmetric Golgi ribbon formation	IMP	19837035
Golgi to plasma membrane protein transport	IBA IMP	19837035

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

leukocyte cell-cell adhesion [inference]

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

post-Golgi vesicle-mediated transport [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cell motility [inference]

cell migration

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to Golgi apparatus [inference]

protein targeting to Golgi apparatus

establishment of protein localization to organelle [inference]

protein targeting to Golgi apparatus

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to Golgi apparatus

protein transport [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of protein localization to organelle [inference]

protein targeting to Golgi apparatus

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

protein retention in Golgi apparatus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to rapamycin

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

cellular response to alcohol [inference]

cellular response to rapamycin

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

cellular response to oxygen-containing compound [inference]

cellular response to ether [inference]

cellular response to rapamycin

cellular response to alcohol [inference]

cellular response to rapamycin

cellular response to ketone [inference]

cellular response to rapamycin

cell adhesion molecule production

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

Golgi organization

Golgi ribbon formation

asymmetric Golgi ribbon formation

vesicle organization [inference]

vesicle budding from membrane [inference]

Golgi vesicle budding

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

plasma membrane bounded cell projection organization [inference]

lamellipodium organization [inference]

lamellipodium assembly

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

membrane organization [inference]

vesicle budding from membrane [inference]

Golgi vesicle budding

export from cell [inference]

secretion by cell [inference]

protein secretion

response to stimulus [inference]

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

response to rapamycin [inference]

cellular response to rapamycin

response to organic cyclic compound [inference]

cellular response to organic cyclic compound [inference]

cellular response to rapamycin

response to rapamycin [inference]

cellular response to rapamycin

response to ether [inference]

cellular response to ether [inference]

cellular response to rapamycin

response to rapamycin [inference]

cellular response to rapamycin

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to rapamycin

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

cellular response to alcohol [inference]

cellular response to rapamycin

response to alcohol [inference]

cellular response to alcohol [inference]

cellular response to rapamycin

response to rapamycin [inference]

cellular response to rapamycin

response to ketone [inference]

response to rapamycin [inference]

cellular response to rapamycin

cellular response to ketone [inference]

cellular response to rapamycin

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to rapamycin

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

cellular response to alcohol [inference]

cellular response to rapamycin

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

cellular response to oxygen-containing compound [inference]

cellular response to ether [inference]

cellular response to rapamycin

cellular response to alcohol [inference]

cellular response to rapamycin

cellular response to ketone [inference]

cellular response to rapamycin

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

response to rapamycin [inference]

cellular response to rapamycin

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

response to oxygen-containing compound [inference]

response to ether [inference]

cellular response to ether [inference]

cellular response to rapamycin

response to rapamycin [inference]

cellular response to rapamycin

response to alcohol [inference]

cellular response to alcohol [inference]

cellular response to rapamycin

response to rapamycin [inference]

cellular response to rapamycin

response to ketone [inference]

response to rapamycin [inference]

cellular response to rapamycin

cellular response to ketone [inference]

cellular response to rapamycin

cellular response to oxygen-containing compound [inference]

cellular response to ether [inference]

cellular response to rapamycin

cellular response to alcohol [inference]

cellular response to rapamycin

cellular response to ketone [inference]

cellular response to rapamycin

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to rapamycin

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

cellular response to alcohol [inference]

cellular response to rapamycin

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to rapamycin

cellular response to oxygen-containing compound [inference]

cellular response to ether [inference]

cellular response to rapamycin

cellular response to alcohol [inference]

cellular response to rapamycin

cellular response to ketone [inference]

cellular response to rapamycin

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to Golgi apparatus [inference]

protein targeting to Golgi apparatus

establishment of protein localization to organelle [inference]

protein targeting to Golgi apparatus

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to Golgi apparatus

protein transport [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of protein localization to organelle [inference]

protein targeting to Golgi apparatus

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

post-Golgi vesicle-mediated transport [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

secretion [inference]

secretion by cell [inference]

protein secretion

organic substance transport [inference]

protein transport [inference]

nitrogen compound transport [inference]

protein transport [inference]

export from cell [inference]

secretion by cell [inference]

protein secretion

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to Golgi apparatus

protein transport [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of protein localization to organelle [inference]

protein targeting to Golgi apparatus

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

protein retention in Golgi apparatus

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

protein retention in Golgi apparatus

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to Golgi apparatus [inference]

protein targeting to Golgi apparatus

establishment of protein localization to organelle [inference]

protein targeting to Golgi apparatus

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to Golgi apparatus

protein transport [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of protein localization to organelle [inference]

protein targeting to Golgi apparatus

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

positive regulation of TOR signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

positive regulation of TOR signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

positive regulation of TOR signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of mitochondrion organization

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

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GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IDA
endosome	IEA
cytosol	IBA IDA	16263763
trans-Golgi network	IBA IDA	16263763 19553991 19837035 23027862
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

Golgi cisterna membrane

bounding membrane of organelle [inference]

Golgi membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

organelle envelope lumen [inference]

mitochondrial intermembrane space

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
enzyme binding	IPI	23027862
phosphatidylinositol-4-phosphate binding	IBA IDA	19837035 23345592
protein binding	IPI	19553991 19837035 22190034 23027862 24485452 25416956
cargo adaptor activity	IDA	34473204

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol-4-phosphate binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

cargo adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000113384

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K15620

Name

golgi phosphoprotein 3

References

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0050012	chikungunya	DisGeNET
DOID:0050387	nonpapillary renal cell carcinoma	DisGeNET
DOID:0050635	alternating hemiplegia of childhood	DisGeNET
DOID:0050819	obsolete Matthew-Wood syndrome	DisGeNET
DOID:0060262	gallbladder disease	DisGeNET
DOID:0060540	Hermansky-Pudlak syndrome 2	DisGeNET
DOID:0060674	catecholaminergic polymorphic ventricular tachycardia	DisGeNET
DOID:0060675	catecholaminergic polymorphic ventricular tachycardia 1	DisGeNET
DOID:0060676	catecholaminergic polymorphic ventricular tachycardia 2	DisGeNET
DOID:0060677	catecholaminergic polymorphic ventricular tachycardia 3	DisGeNET

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	171919	WB:WBGene00021644
Drosophila melanogaster	33402	FB:FBgn0267378
Ciona intestinalis	100180419		CIOIN00627
Callorhinchus milii	103180991		CALMI21646
Latimeria chalumnae	102346954		LATCH03322
Danio rerio	450085	ZFIN:ZDB-GENE-041010-209	DANRE36040
Danio rerio	561662	ZFIN:ZDB-GENE-091117-10
Astyanax mexicanus	103022463		ASTMX06939
Ictalurus punctatus	108255731		ICTPU17150
Electrophorus electricus	113589412		ELEEL01778

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements