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MIRAGE
secreted frizzled related protein 1
Summary
- Gene Symbol
-
- SFRP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Developmental protein
- Differentiation
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Signal
- Wnt signaling pathway
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8N474 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| osteoblast differentiation | ||
| ureteric bud development | ||
| neural tube closure | ||
| positive regulation of cell-matrix adhesion | ||
| hematopoietic progenitor cell differentiation |
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
negative regulation of developmental process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space | ||
| cytosol |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cysteine-type endopeptidase activity | ||
| frizzled binding | ||
| protein binding | ||
| heparin binding | ||
| Wnt-protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Secreted frizzled-related protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| Wnt-protein binding |
| canonical Wnt signaling pathway |
| cell differentiation |
| non-canonical Wnt signaling pathway |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6422 | Xenbase:XB-GENE-488230 | ||
| 20377 | Xenbase:XB-GENE-488230 | MOUSE59049 | |
| 84402 | RATNO11480 | ||
| 282068 | BOVIN22147 | ||
| 702876 | MACMU44728 | ||
| 736186 | PANTR42430 | ||
| 778933 | CIOIN14634 | ||
| 100033009 | MONDO06838 | ||
| 100055845 | HORSE25252 | ||
| 100075380 | ORNAN21109 |
