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signaling receptor and transporter of retinol STRA6

Summary

Gene Symbol

STRA6

Organism

Homo sapiens (human)

External Links

NCBI Gene

64220

PubChem

64220

Alliance of Genome Resources

HGNC:30650

Annotation

Keyword

Alternative splicing
Cell membrane
Disease variant
Glycoprotein
Microphthalmia
Phosphoprotein
Receptor
Reference proteome
Retinol-binding
Transmembrane helix
Transport
Vitamin A

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B3KPB8	Retinol-binding protein receptor STRA6
Q9BX79	Retinol-binding protein receptor STRA6 Stimulated by retinoic acid gene 6 protein homolog

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
neuromuscular process	IMP	17273977
head development	IMP	17273977
eyelid development in camera-type eye	IMP	17273977
pulmonary artery morphogenesis	IMP	17273977
uterus morphogenesis	IMP	17273977

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

vitamin transmembrane transport [inference]

vitamin A import into cell

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

genitalia development [inference]

female genitalia development

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition

learning or memory [inference]

learning

observational learning [inference]

imitative learning [inference]

vocal learning

learned vocalization behavior or vocal learning [inference]

vocal learning

neuromuscular process

behavior [inference]

learning or memory [inference]

learning

observational learning [inference]

imitative learning [inference]

vocal learning

learned vocalization behavior or vocal learning [inference]

vocal learning

feeding behavior

mechanosensory behavior [inference]

auditory behavior [inference]

vocal learning

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

genitalia development [inference]

female genitalia development

anatomical structure morphogenesis [inference]

heart valve morphogenesis [inference]

pulmonary valve morphogenesis

animal organ morphogenesis [inference]

uterus morphogenesis

sensory organ morphogenesis [inference]

nose morphogenesis

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis

digestive tract morphogenesis

anatomical structure formation involved in morphogenesis [inference]

embryonic camera-type eye formation

anatomical structure development [inference]

blood vessel development

cardiac septum development [inference]

ventricular septum development

tissue development [inference]

epithelium development [inference]

lung epithelium development [inference]

alveolar primary septum development

muscle tissue development [inference]

smooth muscle tissue development

tube development [inference]

digestive tract development [inference]

embryonic digestive tract development

paramesonephric duct development

lung alveolus development

animal organ development [inference]

kidney development

sensory organ development [inference]

eye development [inference]

camera-type eye development

ear development

heart development

muscle organ development [inference]

skeletal muscle organ development [inference]

diaphragm development

lung development

embryonic organ development [inference]

embryonic digestive tract development

gland development [inference]

adrenal gland development

genitalia development [inference]

female genitalia development

reproductive structure development [inference]

genitalia development [inference]

female genitalia development

system development [inference]

vasculature development [inference]

lung vasculature development

muscle structure development [inference]

muscle organ development [inference]

skeletal muscle organ development [inference]

diaphragm development

growth [inference]

developmental growth

localization [inference]

establishment of localization [inference]

transport [inference]

vitamin transport [inference]

vitamin transmembrane transport [inference]

vitamin A import into cell

vitamin A transport [inference]

vitamin A import into cell

transmembrane transport [inference]

vitamin transmembrane transport [inference]

vitamin A import into cell

organic substance transport [inference]

lipid transport [inference]

isoprenoid transport [inference]

terpenoid transport [inference]

retinol transport

vitamin A transport [inference]

vitamin A import into cell

lipid import into cell [inference]

vitamin A import into cell

organic hydroxy compound transport [inference]

retinol transport

import into cell [inference]

vitamin A import into cell

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of behavior

regulation of multicellular organismal process [inference]

regulation of behavior [inference]

positive regulation of behavior

positive regulation of multicellular organismal process [inference]

positive regulation of behavior

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein-containing complex	IDA
plasma membrane	IBA IDA TAS	21901792

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183
retinal binding	IEA
retinol transmembrane transporter activity	IDA	21901792
retinol binding	IEA
signaling receptor activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

retinol transmembrane transporter activity

transmembrane transporter activity [inference]

vitamin transmembrane transporter activity [inference]

retinol transmembrane transporter activity

organic hydroxy compound transmembrane transporter activity [inference]

alcohol transmembrane transporter activity [inference]

retinol transmembrane transporter activity

binding [inference]

protein binding

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

small molecule binding [inference]

vitamin binding [inference]

alcohol binding [inference]

retinol binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

STRA6

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
V: Defense mechanisms

Displaying **all 5** entries
Gene Ontology
retinal binding
retinol binding
retinol transmembrane transporter activity
retinol transport
vitamin A import into cell

Displaying 1 entry
InterPro
Receptor for retinol uptake STRA6-like

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050861	colorectal adenocarcinoma	Alliance of Genome Resources
DOID:0111807	syndromic microphthalmia 9	Alliance of Genome Resources
DOID:13641	exfoliation syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 74 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	20897		MGI:107742	MOUSE62148
Rattus norvegicus	363071		RGD:1307551	RATNO41959
Pan troglodytes	453738	9598_0:003e29		PANTR10785
Canis lupus familiaris	611518			CANLF12687
Macaca mulatta	701591			MACMU40878
Danio rerio	724007		ZFIN:ZDB-GENE-060616-252	DANRE46333
Equus caballus	100051799			HORSE17282
Ornithorhynchus anatinus	100076828			ORNAN21637
Xenopus tropicalis	100124902		Xenbase:XB-GENE-1002042
Sus scrofa	100153335			PIGXX32069

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements