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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
colony stimulating factor 1 receptor, a
Summary
- Gene Symbol
-
- csf1ra
- Organism
- Danio rerio (zebrafish)
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Inflammatory response
- Innate immunity
- Magnesium
- Metal-binding
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of xanthophore differentiation | ||
| osteoclast maturation | ||
| regulation of endocytosis | ||
| regulation of osteoclast development | ||
| xanthophore differentiation |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| receptor complex | ||
| plasma membrane | ||
| CSF1-CSF1R complex |
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase activity | ||
| protein binding | ||
| macrophage colony-stimulating factor receptor activity | ||
| metal ion binding | ||
| transmembrane receptor protein tyrosine kinase activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- vascular endothelial growth factor receptor
- Functional Category
-
- K: Transcription
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070343 | CSF1R-related brain malformation and osteopetrosis | |
| DOID:0080006 | bone development disease | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080523 | adult-onset leukoencephalopathy with axonal spheroids and pigmented glia | |
| DOID:10534 | stomach cancer | |
| DOID:13139 | crescentic glomerulonephritis | |
| DOID:1324 | lung cancer | |
| DOID:1612 | breast cancer | |
| DOID:234 | colon adenocarcinoma | |
| DOID:3744 | cervical squamous cell carcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 1436 | HGNC:2433 | HUMAN81677 | ||
| 12978 | MGI:1339758 | MOUSE23367 | ||
| 175182 | WB:WBGene00006894 | |||
| 307403 | RGD:2425 | RATNO13472 | ||
| 462187 | PANTR36554 | |||
| 489188 | CANLF14927 | |||
| 493543 | Xenbase:XB-GENE-6257851 | |||
| 493706 | FELCA00791 | |||
| 509418 | BOVIN33740 | |||
| 711512 | MACMU37953 |
