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MIRAGE
inverted formin 2
Summary
- Gene Symbol
-
- INF2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Actin-binding
- Alternative splicing
- Charcot-Marie-Tooth disease
- Coiled coil
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Neurodegeneration
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q27J81 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin filament polymerization | ||
| regulation of mitochondrial fission |
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin filament | ||
| perinuclear region of cytoplasm |
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding | ||
| protein binding | ||
| small GTPase binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- inverted formin-2
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| actin binding |
| actin cytoskeleton organization |
| InterPro |
|---|
| Formin, FH2 domain superfamily |
| Formin, FH2 domain |
| Inverted formin-2 |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110205 | Charcot-Marie-Tooth disease dominant intermediate E | |
| DOID:0111130 | focal segmental glomerulosclerosis 5 |
