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nischarin

Summary

Gene Symbol

Nisch

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

64652

PubChem

64652

Alliance of Genome Resources

MGI:1928323

Annotation

Keyword

Alternative splicing
Apoptosis
Cell membrane
Coiled coil
Cytoplasm
Endosome
Leucine-rich repeat
Phosphoprotein
Receptor
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q80TM9	Imidazoline receptor 1 Imidazoline receptor I-1-like protein Imidazoline-1 receptor
Q8CF63

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
actin cytoskeleton organization	IDA	11121431
negative regulation of cell migration	IDA	11121431
Rac protein signal transduction	IDA	11121431
apoptotic process	IEA
norepinephrine secretion	ISO

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction [inference]

Rac protein signal transduction

cell death [inference]

programmed cell death [inference]

apoptotic process

actin filament-based process [inference]

actin cytoskeleton organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

cellular component assembly [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly [inference]

outer dynein arm assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly [inference]

outer dynein arm assembly

export from cell [inference]

secretion by cell [inference]

signal release [inference]

norepinephrine secretion

catecholamine secretion [inference]

norepinephrine secretion

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

signal release [inference]

norepinephrine secretion

catecholamine secretion [inference]

norepinephrine secretion

organic substance transport [inference]

organic cation transport [inference]

norepinephrine transport [inference]

norepinephrine secretion

monoamine transport [inference]

catecholamine transport [inference]

norepinephrine transport [inference]

norepinephrine secretion

catecholamine secretion [inference]

norepinephrine secretion

organic hydroxy compound transport [inference]

catecholamine transport [inference]

norepinephrine transport [inference]

norepinephrine secretion

catecholamine secretion [inference]

norepinephrine secretion

nitrogen compound transport [inference]

monoamine transport [inference]

catecholamine transport [inference]

norepinephrine transport [inference]

norepinephrine secretion

catecholamine secretion [inference]

norepinephrine secretion

export from cell [inference]

secretion by cell [inference]

signal release [inference]

norepinephrine secretion

catecholamine secretion [inference]

norepinephrine secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, GABAergic

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction [inference]

Rac protein signal transduction

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, GABAergic

negative regulation of cellular process [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of biological quality [inference]

regulation of blood pressure

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
recycling endosome	IEA
early endosome	IEA
intracellular membrane-bounded organelle	ISO
plasma membrane	IEA ISO
nucleoplasm	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

intercellular bridge

Displaying **all 5** entries
GO Term	Evidence Code	PMID
integrin binding	IDA	11121431
phosphatidylinositol binding	IEA
identical protein binding	IEA ISO
dynein heavy chain binding	IBA
alpha-tubulin binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

alpha-tubulin binding

cell adhesion molecule binding [inference]

integrin binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

nischarin

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
P: Inorganic ion transport and metabolism

Displaying **all 2** entries
Gene Ontology
integrin binding
phosphatidylinositol binding

Displaying **all 5** entries
InterPro
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat
PX domain superfamily
Phox homology

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:10754	otitis media	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:6000	congestive heart failure	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **104** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	11188		HGNC:18006	HUMAN70474
Drosophila melanogaster	36683		FB:FBgn0033996
Caenorhabditis elegans	177981		WB:WBGene00008750
Rattus norvegicus	306255	10116_1:0049fc	RGD:1306950	RATNO11140
Danio rerio	553087		ZFIN:ZDB-GENE-050208-570
Macaca mulatta	696916			MACMU27823
Pan troglodytes	745886			PANTR31309
Equus caballus	100060179			HORSE11813
Ornithorhynchus anatinus	100074337			ORNAN28946
Sus scrofa	100156417			PIGXX04224

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements