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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
WNK lysine deficient protein kinase 1
Summary
- Gene Symbol
-
- WNK1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative promoter usage
- Alternative splicing
- Chloride
- Cytoskeleton
- Direct protein sequencing
- Glycoprotein
- Kinase
- Neurodegeneration
- Neuropathy
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Serine/threonine-protein kinase
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of GTPase activity | ||
| regulation of mRNA export from nucleus | ||
| negative regulation of cell-cell adhesion mediated by integrin | ||
| cell volume homeostasis | ||
| negative regulation of pancreatic juice secretion |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular localization [inference]
regulation of cell motility [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| protein serine kinase activity | ||
| phosphatase binding | ||
| protein serine/threonine kinase activity | ||
| protein kinase binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Kinase
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| kinase activity |
| nucleotide binding |
| phosphorylation |
| InterPro |
|---|
| Protein kinase domain |
| Protein kinase-like domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050548 | hereditary sensory neuropathy | |
| DOID:0070155 | hereditary sensory and autonomic neuropathy type 2A | |
| DOID:10763 | hypertension | |
| DOID:224 | transient cerebral ischemia | |
| DOID:4479 | pseudohypoaldosteronism |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 40391 | FB:FBgn0037098 | |||
| 116477 | RGD:621141 | RATNO29968 | ||
| 177743 | WB:WBGene00006941 | |||
| 232341 | MGI:2442092 | MOUSE50780 | ||
| 451739 | 9598_0:003446 | PANTR04805 | ||
| 477728 | CANLF11208 | |||
| 561159 | ZFIN:ZDB-GENE-030131-2656 | DANRE34464 | ||
| 706493 | MACMU04005 | |||
| 733420 | Xenbase:XB-GENE-991150 | |||
| 100017207 | MONDO33456 |
