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MIRAGE
protocadherin related 15
Summary
- Gene Symbol
-
- PCDH15
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cell adhesion
- Cell membrane
- Coiled coil
- Disease variant
- Disulfide bond
- Glycoprotein
- Hearing
- Non-syndromic deafness
- Proteomics identification
- Reference proteome
- Repeat
- Retinitis pigmentosa
- Secreted
- Signal
- Transmembrane helix
- Usher syndrome
- Proteins
| UniProt | Protein Name |
|---|---|
| A9Z1W1 |
|
| E7EM53 |
|
| A2A3E6 |
|
| A2A3E7 |
|
| A0A087WZN9 |
|
| Q96QU1 |
|
| A2A3D8 |
|
| A0A087X1T6 |
|
| A2A3E8 |
|
| A0A087WTR6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell adhesion | ||
| homophilic cell adhesion via plasma membrane adhesion molecules | ||
| sensory perception of sound | ||
| photoreceptor cell maintenance | ||
| inner ear development |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| photoreceptor outer segment | ||
| extracellular region | ||
| extracellular space | ||
| plasma membrane | ||
| stereocilium |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Protocadherin-15
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| calcium ion binding |
| homophilic cell adhesion via plasma membrane adhesion molecules |
| InterPro |
|---|
| Cadherin conserved site |
| Cadherin-like superfamily |
| Cadherin-like |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110481 | autosomal recessive nonsyndromic deafness 23 | |
| DOID:0110831 | Usher syndrome type 1D | |
| DOID:0110832 | Usher syndrome type 1F |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 11994 | Xenbase:XB-GENE-986760 | MOUSE02246 | |
| 43528 | ZFIN:ZDB-GENE-050214-1 | ||
| 65217 | Xenbase:XB-GENE-986760 | ||
| 368476 | DANRE05301 | ||
| 450468 | PANTR00657 | ||
| 609280 | CANLF10654 | ||
| 690865 | RATNO21963 | ||
| 702413 | MACMU46406 | ||
| 100023993 | MONDO01683 | ||
| 100140108 | BOVIN21091 |
