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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
solute carrier family 6 member 2
Summary
- Gene Symbol
-
- SLC6A2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Metal-binding
- Neurotransmitter transport
- Reference proteome
- Sodium
- Symport
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P23975 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| norepinephrine transport | ||
| response to xenobiotic stimulus | ||
| response to pain | ||
| dopamine uptake involved in synaptic transmission | ||
| monoamine transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| synaptic vesicle membrane | ||
| membrane | ||
| neuronal cell body membrane | ||
| plasma membrane | ||
| cell surface |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| actin binding | ||
| monoamine transmembrane transporter activity | ||
| metal ion binding | ||
| norepinephrine:sodium symporter activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Transporter
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| symporter activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:0070489 | classic dopamine transporter deficiency syndrome | |
| DOID:0090145 | dopamine beta-hydroxylase deficiency | |
| DOID:10273 | heart conduction disease | |
| DOID:10763 | hypertension | |
| DOID:1094 | attention deficit hyperactivity disorder | |
| DOID:11569 | neurocirculatory asthenia | |
| DOID:1596 | depressive disorder |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 20538 | MGI:1270850 | MOUSE59237 | ||
| 36849 | FB:FBgn0034136 | |||
| 83511 | RGD:621822 | RATNO15326 | ||
| 176304 | WB:WBGene00000934 | |||
| 282363 | BOVIN10455 | |||
| 454096 | 9598_0:0040e0 | PANTR12381 | ||
| 487272 | CANLF06837 | |||
| 565776 | ZFIN:ZDB-GENE-110408-4 | DANRE40793 | ||
| 613238 | MACMU26423 | |||
| 100020675 | MONDO07368 |
