GlyCosmos Portal

Submissions

solute carrier family 6 member 9

Summary

Gene Symbol

SLC6A9

Organism

Homo sapiens (human)

External Links

NCBI Gene

6536

PubChem

6536

Alliance of Genome Resources

HGNC:11056

JoGo

SLC6A9

TogoVar

SLC6A9

Annotation

Keyword

3D-structure
Alternative splicing
Amino-acid transport
Cell membrane
Disease variant
Disulfide bond
Metal-binding
Neurotransmitter transport
Phosphoprotein
Proteomics identification
Reference proteome
Sodium
Symport
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
B7Z3A9	Solute carrier family 6 member 9
B7Z3W8	Solute carrier family 6 member 9
P48067	Solute carrier family 6 member 9
B7Z589	Solute carrier family 6 member 9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
neurotransmitter transport	IEA
glycine transport	ISS
glycine transport	IEA
sodium ion transmembrane transport	IBA
positive regulation of hemoglobin biosynthetic process	ISS

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glycinergic

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

neurotransmitter transport

vascular transport [inference]

transport across blood-brain barrier

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

neutral amino acid transport [inference]

glycine transport

glycine import across plasma membrane

L-amino acid transport [inference]

glycine transport

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

neutral amino acid transport [inference]

glycine transport

glycine import across plasma membrane

L-amino acid transport [inference]

glycine transport

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

nitrogen compound transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

neutral amino acid transport [inference]

glycine transport

glycine import across plasma membrane

L-amino acid transport [inference]

glycine transport

glycine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

glycine import across plasma membrane

import into cell [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

regulation of hemoglobin biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of tetrapyrrole biosynthetic process [inference]

regulation of heme biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

regulation of hemoglobin biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of tetrapyrrole biosynthetic process [inference]

regulation of heme biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of tetrapyrrole biosynthetic process [inference]

regulation of heme biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of protein metabolic process [inference]

regulation of hemoglobin biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of hemoglobin biosynthetic process

regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of tetrapyrrole biosynthetic process [inference]

regulation of heme biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

regulation of hemoglobin biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of hemoglobin biosynthetic process

regulation of protein metabolic process [inference]

regulation of hemoglobin biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of hemoglobin biosynthetic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of hemoglobin biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of hemoglobin biosynthetic process

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity [inference]

regulation of neurotransmitter receptor activity [inference]

regulation of NMDA receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, glycinergic

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glycinergic

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of NMDA receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of monoatomic ion transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity [inference]

regulation of neurotransmitter receptor activity [inference]

regulation of NMDA receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity [inference]

regulation of neurotransmitter receptor activity [inference]

regulation of NMDA receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, glycinergic

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

regulation of hemoglobin biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of tetrapyrrole biosynthetic process [inference]

regulation of heme biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of tetrapyrrole biosynthetic process [inference]

regulation of heme biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of NMDA receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of hemoglobin biosynthetic process

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

positive regulation of tetrapyrrole metabolic process [inference]

positive regulation of tetrapyrrole biosynthetic process [inference]

positive regulation of heme biosynthetic process

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of molecular function [inference]

regulation of signaling receptor activity [inference]

regulation of neurotransmitter receptor activity [inference]

regulation of NMDA receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of transporter activity [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

regulation of NMDA receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of molecular function [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of NMDA glutamate receptor activity

negative regulation of signaling receptor activity [inference]

negative regulation of NMDA glutamate receptor activity

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
endosome	ISS
plasma membrane	ISS
plasma membrane	TAS
plasma membrane	IBA
basal plasma membrane	IDA	11159884

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

plasma membrane region [inference]

synaptic membrane [inference]

lateral plasma membrane

cell junction [inference]

synapse [inference]

excitatory synapse [inference]

parallel fiber to Purkinje cell synapse

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

secretory vesicle [inference]

secretory granule [inference]

dense core granule

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

secretory vesicle [inference]

secretory granule [inference]

dense core granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

secretory vesicle [inference]

secretory granule [inference]

dense core granule

postsynaptic specialization [inference]

postsynaptic density

Displaying **all 5** entries
GO Term	Evidence Code	PMID
amino acid:sodium symporter activity	IBA
glycine transmembrane transporter activity	ISS
glycine transmembrane transporter activity	TAS	11159884
glycine:sodium symporter activity	TAS
glycine:sodium symporter activity	IDA	8183239