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tectonic family member 1

Summary

Gene Symbol

Tctn1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

654470

PubChem

654470

Alliance of Genome Resources

MGI:3603820

Annotation

Keyword

Alternative splicing
Cell projection
Cilium biogenesis/degradation
Cytoskeleton
Developmental protein
Glycoprotein
Methylation
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BZ64

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
regulation of smoothened signaling pathway	IMP	16357211
neural tube formation	IMP	16357211
central nervous system interneuron axonogenesis	IMP	16357211
in utero embryonic development	IMP	16357211

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in spinal cord [inference]

spinal cord motor neuron differentiation [inference]

somatic motor neuron differentiation

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

spinal cord motor neuron differentiation [inference]

somatic motor neuron differentiation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium [inference]

protein localization to ciliary transition zone

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis [inference]

central nervous system neuron axonogenesis [inference]

central nervous system interneuron axonogenesis

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

pattern specification process [inference]

regionalization [inference]

dorsal/ventral pattern formation [inference]

dorsal/ventral neural tube patterning

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis [inference]

central nervous system neuron axonogenesis [inference]

central nervous system interneuron axonogenesis

anatomical structure formation involved in morphogenesis [inference]

tube formation [inference]

epithelial tube formation [inference]

embryonic epithelial tube formation [inference]

neural tube formation

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

telencephalon development

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in spinal cord [inference]

spinal cord motor neuron differentiation [inference]

somatic motor neuron differentiation

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

spinal cord motor neuron differentiation [inference]

somatic motor neuron differentiation

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium [inference]

protein localization to ciliary transition zone

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium [inference]

protein localization to ciliary transition zone

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
membrane	IDA	22179047
MKS complex	IBA IDA	21725307 22179047
ciliary transition zone	IMP	21725307
extracellular space	IDA	16357211
cytoskeleton	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

MKS complex

cellular anatomical entity [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	21565611 22179047

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Tectonic

Functional Category

G: Carbohydrate transport and metabolism
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cell projection organization
protein localization to ciliary transition zone

Displaying **all 2** entries
InterPro
Tectonic domain
Tectonic

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110982	Joubert syndrome 13	Alliance of Genome Resources

Ortholog

Displaying entries **61 - 70** of **103** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Equus asinus asinus	106842275		EQUAS13921
Marmota marmota marmota	107156433	9994_0:00340f
Ictalurus punctatus	108277363		ICTPU08564
Rhinopithecus bieti	108512278		RHIBE02803
Cyprinus carpio carpio	109097797		CYPCA132181
Crocodylus porosus	109312648		CROPO19320
Castor canadensis	109696009	51338_0:0034bc
Phascolarctos cinereus	110196824		PHACI07608
Mus caroli	110294682	10089_0:001818
Mus pahari	110312808	10093_0:0049b4

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements