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solute carrier family 8 member A3
Summary
- Gene Symbol
-
- SLC8A3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Antiport
- Calcium transport
- Calmodulin-binding
- Cell junction
- Cell membrane
- Cell projection
- Cytoplasm
- Endoplasmic reticulum
- Glycoprotein
- Metal-binding
- Mitochondrion outer membrane
- Reference proteome
- Repeat
- Signal
- Sodium transport
- Synapse
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| oligodendrocyte differentiation | ||
| cell communication | ||
| regulation of skeletal muscle contraction | ||
| regulation of cardiac conduction | ||
| myelination |
GO Hierarchy
biological process
cellular process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| axon terminus | ||
| anchoring junction | ||
| sarcolemma | ||
| postsynaptic density | ||
| postsynapse |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| calmodulin binding | ||
| calcium:sodium antiporter activity | ||
| monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential |
|
|
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Sodium/calcium exchanger
- Functional Category
-
- E: Amino acid transport and metabolism
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium ion transport |
| calcium |
| calmodulin binding |
| cell communication |
| metal ion binding |
| monoatomic ion transport |
| sodium ion transmembrane transport |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease | |
| DOID:1824 | status epilepticus | |
| DOID:2316 | brain ischemia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 42481 | FB:FBgn0013995 | |||
| 110893 | MGI:107976 | MOUSE09358 | ||
| 140448 | RGD:620197 | RATNO35146 | ||
| 178918 | WB:WBGene00003567 | |||
| 446366 | Xenbase:XB-GENE-954538 | |||
| 467491 | 9598_0:003b10 | PANTR09060 | ||
| 490755 | CANLF18038 | |||
| 540307 | BOVIN01629 | |||
| 560561 | ZFIN:ZDB-GENE-050810-1 | DANRE05461 | ||
| 713061 | MACMU40441 |
