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solute carrier family 20 member 2

Summary

Gene Symbol

SLC20A2

Organism

Homo sapiens (human)

External Links

NCBI Gene

6575

PubChem

6575

Alliance of Genome Resources

HGNC:10947

Annotation

Keyword

Cell membrane
Disease variant
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Phosphate transport
Phosphoprotein
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q08357	Gibbon ape leukemia virus receptor 2 Phosphate transporter 2 Solute carrier family 20 member 2
B4DJ71
B2RBR4
A0A384MR38

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
positive regulation of bone mineralization	ISS
monoatomic ion transport	TAS
ion transport	TAS
viral entry into host cell	IEA
sodium ion transmembrane transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

phosphate ion transmembrane transport

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

localization [inference]

establishment of localization [inference]

transport [inference]

ion transport

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic anion transport [inference]

phosphate ion transport [inference]

phosphate ion transmembrane transport

inorganic anion transmembrane transport [inference]

phosphate ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

phosphate ion transmembrane transport

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

positive regulation of multicellular organismal process [inference]

positive regulation of ossification [inference]

positive regulation of bone mineralization

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

regulation of multicellular organismal process [inference]

regulation of ossification [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of ossification [inference]

positive regulation of bone mineralization

positive regulation of multicellular organismal process [inference]

positive regulation of ossification [inference]

positive regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	TAS	8302848
apical plasma membrane	ISS
plasma membrane	IMP TAS	28722801 30704756
brush border membrane	ISS
extracellular exosome	HDA	19199708

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
inorganic phosphate transmembrane transporter activity	IBA
signaling receptor activity	TAS	8302848
sodium:phosphate symporter activity	IDA IMP TAS	12205090 15955065 16790504 17494632 22327515 28722801 30704756
virus receptor activity	IMP	12205090 15955065

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic phosphate transmembrane transporter activity

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

inorganic phosphate transmembrane transporter activity

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

binding [inference]

protein binding [inference]

exogenous protein binding [inference]

virus receptor activity

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

PHOSPHATE TRANSPORTER

Functional Category

M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism
V: Defense mechanisms

Displaying **all 5** entries
Gene Ontology
inorganic ion transmembrane transport
phosphate ion transmembrane transport
phosphate ion transport
sodium
symporter activity

Displaying 1 entry
InterPro
Phosphate transporter

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060230	basal ganglia calcification	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 96 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	20516	MGI:97851	MOUSE58514
Rattus norvegicus	29502	RGD:3699	RATNO11411
Drosophila melanogaster	39255	FB:FBgn0260795
Caenorhabditis elegans	174883	WB:WBGene00012285
Caenorhabditis elegans	177512	WB:WBGene00016739
Caenorhabditis elegans	179104	WB:WBGene00017312
Caenorhabditis elegans	179355	WB:WBGene00007141
Caenorhabditis elegans	181857	WB:WBGene00015054
Caenorhabditis elegans	181858	WB:WBGene00015055
Canis lupus familiaris	482838		CANLF04650