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solute carrier family 20 member 2

Summary

Gene Symbol

SLC20A2

Organism

Homo sapiens (human)

External Links

NCBI Gene

6575

PubChem

6575

Alliance of Genome Resources

HGNC:10947

Annotation

Keyword

Cell membrane
Disease variant
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Phosphate transport
Phosphoprotein
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q08357	Gibbon ape leukemia virus receptor 2 Phosphate transporter 2 Solute carrier family 20 member 2
B4DJ71
B2RBR4
A0A384MR38

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
ion transport	TAS
monoatomic ion transport	TAS
positive regulation of bone mineralization	ISS
phosphate ion transmembrane transport	IBA
sodium ion transmembrane transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

phosphate ion transmembrane transport

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic anion transport [inference]

phosphate ion transport [inference]

phosphate ion transmembrane transport

inorganic anion transmembrane transport [inference]

phosphate ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

phosphate ion transmembrane transport

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

positive regulation of multicellular organismal process [inference]

positive regulation of ossification [inference]

positive regulation of bone mineralization

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

regulation of multicellular organismal process [inference]

regulation of ossification [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of ossification [inference]

positive regulation of bone mineralization

positive regulation of multicellular organismal process [inference]

positive regulation of ossification [inference]

positive regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IMP	28722801 30704756
membrane	TAS	8302848
apical plasma membrane	ISS
brush border membrane	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
virus receptor activity	IMP	12205090 15955065
inorganic phosphate transmembrane transporter activity	IBA
sodium:phosphate symporter activity	TAS
sodium:phosphate symporter activity	IDA	17494632
sodium:phosphate symporter activity	IMP	12205090 15955065 16790504 22327515 28722801 30704756

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic phosphate transmembrane transporter activity

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

inorganic phosphate transmembrane transporter activity

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

binding [inference]

protein binding [inference]

exogenous protein binding [inference]

virus receptor activity

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phosphate transporter

Functional Category

M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism
V: Defense mechanisms

Displaying **all 4** entries
Gene Ontology
phosphate ion transmembrane transport
phosphate ion transport
sodium
symporter activity

Displaying 1 entry
InterPro
Phosphate transporter

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060230	basal ganglia calcification	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 88 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	6574	SGD:S000000500
Xenopus tropicalis	6575	Xenbase:XB-GENE-1015057
Mus musculus	20516	Xenbase:XB-GENE-1015057	MOUSE58514
Rattus norvegicus	29502	Xenbase:XB-GENE-1015057	RATNO11411
Canis lupus familiaris	482838		CANLF04650
Felis catus	493788		FELCA08946
Xenopus tropicalis	495011	Xenbase:XB-GENE-1015057
Bos taurus	518905		BOVIN22169
Xenopus tropicalis	549658	Xenbase:XB-GENE-1015057
Danio rerio	558346		DANRE42778