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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
solute carrier family 22 member 1
Summary
- Gene Symbol
-
- SLC22A1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Glycoprotein
- Ion transport
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O15245 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| xenobiotic transport across blood-brain barrier | ||
| monoatomic cation transmembrane transport | ||
| acyl carnitine transmembrane transport | ||
| dopamine uptake | ||
| serotonin transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| lateral plasma membrane | ||
| presynapse | ||
| apical plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| monoamine transmembrane transporter activity | ||
| secondary active organic cation transmembrane transporter activity |
|
|
| organic anion transmembrane transporter activity | ||
| quaternary ammonium group transmembrane transporter activity |
GO Hierarchy
molecular function
transporter activity [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- transporter
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| MFS transporter superfamily |
| Major facilitator superfamily domain |
| Major facilitator, sugar transporter-like |
| Sugar transporter, conserved site |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:13619 | extrahepatic cholestasis | |
| DOID:1852 | intrahepatic cholestasis | |
| DOID:2841 | asthma | |
| DOID:3021 | acute kidney failure |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 20517 | MGI:108111 | MOUSE21259 | ||
| 24904 | RGD:3224 | RATNO19318 | ||
| 35334 | FB:FBgn0032879 | |||
| 36417 | FB:FBgn0033778 | |||
| 36458 | FB:FBgn0033809 | |||
| 38689 | FB:FBgn0259164 | |||
| 40437 | FB:FBgn0037140 | |||
| 40441 | FB:FBgn0037144 | |||
| 41967 | FB:FBgn0038407 | |||
| 42606 | FB:FBgn0038938 |
