GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein serine/threonine kinase activity	IDA	12065756
transmembrane receptor protein serine/threonine kinase activity	NAS	10051328
transmembrane signaling receptor activity	IDA	18184661
transforming growth factor beta receptor activity, type I	IBA
transforming growth factor beta receptor activity, type II	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

transmembrane receptor protein serine/threonine kinase activity

transforming growth factor beta receptor activity [inference]

activin receptor activity [inference]

BMP receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity

transforming growth factor beta receptor activity [inference]

activin receptor activity [inference]

BMP receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

transmembrane receptor protein serine/threonine kinase activity

transforming growth factor beta receptor activity [inference]

activin receptor activity [inference]

BMP receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity

transforming growth factor beta receptor activity [inference]

activin receptor activity [inference]

BMP receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

transmembrane receptor protein serine/threonine kinase activity

transforming growth factor beta receptor activity [inference]

activin receptor activity [inference]

BMP receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity

transforming growth factor beta receptor activity [inference]

activin receptor activity [inference]

BMP receptor activity

binding [inference]

protein binding

cytokine binding [inference]

BMP binding

SMAD binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity

transforming growth factor beta receptor activity [inference]

activin receptor activity [inference]

BMP receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

kinase

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ATP binding
nucleotide binding
transmembrane receptor protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase signaling pathway

Displaying **all 6** entries
InterPro
GS domain
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Ser/Thr protein kinase, TGFB receptor
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0081237	acromesomelic dysplasia 3	Alliance of Genome Resources
DOID:0110965	brachydactyly type A2	Alliance of Genome Resources
DOID:0110978	brachydactyly type A1D	Alliance of Genome Resources
DOID:2256	osteochondrodysplasia	Alliance of Genome Resources

Ortholog

Displaying entries **101 - 102** of **102** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Panthera leo	122218030		PANLE27172
Ursus americanus	123788609		URSAM13813

GlyTouCan

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements