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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ADAM metallopeptidase with thrombospondin type 1 motif, 4
Summary
- Gene Symbol
-
- Adamts4
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9ESP7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| extracellular matrix organization | ||
| defense response to bacterium |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| nuclear speck | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| zinc ion binding | ||
| protease binding | ||
| metalloendopeptidase activity | ||
| metallopeptidase activity | ||
| peptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Thrombospondin type-1 (TSP1) repeat
- Functional Category
-
- I: Lipid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- P: Inorganic ion transport and metabolism
- U: Intracellular trafficking, secretion, and vesicular transport
| Gene Ontology |
|---|
| extracellular matrix organization |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 9507 | HGNC:220 | HUMAN53168 | ||
| 41887 | FB:FBgn0286071 | |||
| 177850 | WB:WBGene00001650 | |||
| 240913 | 10090_1:000448 | MGI:1339949 | MOUSE30178 | |
| 286806 | BOVIN25529 | |||
| 457453 | PANTR22807 | |||
| 488651 | CANLF14413 | |||
| 719927 | MACMU24348 | |||
| 100008765 | RABIT03178 | |||
| 100032755 | MONDO11793 |
