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MIRAGE
synaptosome associated protein 25
Summary
- Gene Symbol
-
- SNAP25
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Coiled coil
- Cytoplasm
- Disease variant
- Epilepsy
- Intellectual disability
- Palmitate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Synaptosome
- Proteins
| UniProt | Protein Name |
|---|---|
| P60880 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| neurotransmitter uptake | ||
| exocytosis | ||
| chemical synaptic transmission | ||
| axonogenesis | ||
| long-term memory |
GO Hierarchy
biological process
cellular process [inference]
localization [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated potassium channel activity | ||
| SNAP receptor activity | ||
| protein binding | ||
| lipid binding | ||
| myosin binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- synaptosomal-associated protein
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| synaptic vesicle fusion to presynaptic active zone membrane |
| synaptic vesicle priming |
| InterPro |
|---|
| SNAP-25 domain |
| Target SNARE coiled-coil homology domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110683 | congenital myasthenic syndrome 18 | |
| DOID:14250 | Down syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6616 | Xenbase:XB-GENE-948769 | ||
| 8773 | SGD:S000003241 | ||
| 20614 | Xenbase:XB-GENE-948769 | MOUSE35496 | |
| 25012 | RATNO27226 | ||
| 30711 | DANRE12264 | ||
| 30712 | DANRE19151 | ||
| 458096 | PANTR24359 | ||
| 477158 | CANLF09299 | ||
| 540853 | BOVIN04215 | ||
| 574204 | MACMU00636 |
