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synuclein beta

Summary

Gene Symbol

SNCB

Organism

Homo sapiens (human)

External Links

NCBI Gene

6620

PubChem

6620

Alliance of Genome Resources

HGNC:11140

Annotation

Keyword

Cytoplasm
Direct protein sequencing
Phosphoprotein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 3** entries
UniProt	Protein Name
G4Y815
Q16143
G4Y816

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
chemical synaptic transmission	IBA
dopamine metabolic process	IEA
negative regulation of neuron apoptotic process	IEA
synaptic vesicle endocytosis	IBA
synapse organization	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

vesicle-mediated transport [inference]

endocytosis [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

import into cell [inference]

endocytosis [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of localization in cell [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasm	IBA
cytosol	TAS
inclusion body	IDA	17222866
neuronal cell body	IBA
axon terminus	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus

presynapse [inference]

axon terminus

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
phospholipase inhibitor activity	TAS	9806846
calcium ion binding	IDA	11312271
protein binding	IPI	32296183 32814053
transition metal ion binding	IMP	25495902
cuprous ion binding	IMP	25495902

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding

copper ion binding [inference]

cuprous ion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

lipase inhibitor activity [inference]

phospholipase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

lipase inhibitor activity [inference]

phospholipase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

synuclein beta

Functional Category

I: Lipid transport and metabolism
K: Transcription
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
chemical synaptic transmission
cuprous ion binding
synapse organization

Displaying **all 2** entries
InterPro
Beta-synuclein
Synuclein

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:12217	Lewy body dementia	Alliance of Genome Resources
DOID:14330	Parkinson's disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 54 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	6620	Xenbase:XB-GENE-973307
Mus musculus	104069	Xenbase:XB-GENE-973307	MOUSE11180
Rattus norvegicus	113893	Xenbase:XB-GENE-973307	RATNO12377
Canis lupus familiaris	479279		CANLF14784
Bos taurus	508421		BOVIN33143
Macaca mulatta	697484		MACMU38172
Pan troglodytes	736255		PANTR36905
Sus scrofa	100127169		PIGXX19201
Callithrix jacchus	100410405		CALJA26776
Pongo abelii	100456125		PONAB28982

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements