synuclein alpha

Summary
Gene Symbol
  • SNCA
Organism
Homo sapiens (human)
NCBI Gene
6622
PubChem
6622
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Alzheimer disease
  • Amyloid
  • Cell projection
  • Copper
  • Cytoplasm
  • Direct protein sequencing
  • Disease variant
  • Membrane
  • Metal-binding
  • Neurodegeneration
  • Nucleus
  • Parkinson disease
  • Parkinsonism
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Secreted
  • Synapse
  • Ubl conjugation
Proteins
Displaying all 2 entries
UniProt Protein Name
P37840
  • Non-A beta component of AD amyloid
  • Non-A4 component of amyloid precursor
H6UYS5
Gene Ontology (GO)
GO Hierarchy
Displaying entries 1 - 5 of 22 in total
GO Term Evidence Code PMID
axon terminus
synaptic vesicle membrane
membrane
cell cortex
postsynapse
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
synuclein alpha
Functional Category
  • K: Transcription
  • P: Inorganic ion transport and metabolism
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying entries 1 - 10 of 16 in total
DO ID Disease Name Source
DOID:0060367 Parkinson's disease 1
DOID:0060895 Parkinson's disease 4
DOID:10652 Alzheimer's disease
DOID:11870 Pick's disease
DOID:11949 Creutzfeldt-Jakob disease
DOID:12217 Lewy body dementia
DOID:14330 Parkinson's disease
DOID:1596 depressive disorder
DOID:3192 neurilemmoma
DOID:3312 bipolar disorder

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024