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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
fascin actin-bundling protein 1
Summary
- Gene Symbol
-
- FSCN1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Actin-binding
- Cell junction
- Cell projection
- Cytoskeleton
- Direct protein sequencing
- Isopeptide bond
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A384MEG1 |
|
| Q16658 |
|
| B3KTA3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin cytoskeleton organization | ||
| positive regulation of podosome assembly | ||
| parallel actin filament bundle assembly | ||
| positive regulation of lamellipodium assembly | ||
| cell migration |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell cortex | ||
| cell projection membrane | ||
| microspike | ||
| microvillus | ||
| filopodium |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| actin binding | ||
| actin filament binding | ||
| protein-macromolecule adaptor activity | ||
| RNA binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- fascin
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| actin binding |
| actin filament binding |
| actin filament organization |
| cell migration |
| protein-macromolecule adaptor activity |
| InterPro |
|---|
| Actin-crosslinking |
| Fascin domain |
| Fascin, metazoans |
| Fascin |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14086 | MGI:1352745 | MOUSE46992 | ||
| 31717 | FB:FBgn0003447 | |||
| 394733 | Xenbase:XB-GENE-488979 | |||
| 397934 | Xenbase:XB-GENE-488983 | |||
| 446226 | Xenbase:XB-GENE-17346730 | |||
| 463247 | 9598_0:0022e0 | PANTR39649 | ||
| 489880 | CANLF16298 | |||
| 507342 | BOVIN21001 | |||
| 558271 | ZFIN:ZDB-GENE-031009-1 | DANRE31370 | ||
| 570314 | ZFIN:ZDB-GENE-120507-1 |
