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SUMO1/sentrin specific peptidase 7

Summary

Gene Symbol

Senp7

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

66315

PubChem

66315

Alliance of Genome Resources

MGI:1913565

Annotation

Keyword

Cytoplasm
Innate immunity
Phosphoprotein
Protease
Proteomics identification
Reference proteome
Thiol protease
Ubl conjugation pathway

Proteins

Displaying **all 6** entries
UniProt	Protein Name
Q9CQN9
Q8BUH8	SUMO-1-specific protease 2 Sentrin/SUMO-specific protease SENP7
E9Q1L5
A0A0J9YUC9
Q9CX65
Q3TPI1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
proteolysis	IEA
protein desumoylation	IDA	28095500
protein desumoylation	IBA
antiviral innate immune response	IDA	28095500

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response [inference]

antiviral innate immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein desumoylation

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein desumoylation

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein desumoylation

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein desumoylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein desumoylation

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein desumoylation

macromolecule modification [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein desumoylation

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein desumoylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein desumoylation

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein desumoylation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

antiviral innate immune response

defense response to other organism [inference]

innate immune response [inference]

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

antiviral innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response [inference]

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

antiviral innate immune response

immune response [inference]

innate immune response [inference]

antiviral innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

antiviral innate immune response

defense response to other organism [inference]

innate immune response [inference]

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

antiviral innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

antiviral innate immune response

defense response to other organism [inference]

innate immune response [inference]

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

antiviral innate immune response

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleus	ISO
nucleus	IBA
nucleus	IEA
cytoplasm	IDA	28095500
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

cytosol [inference]

cytosolic region [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	22388734
SUMO-specific endopeptidase activity	IDA	28095500
SUMO-specific endopeptidase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

cysteine-type endopeptidase activity [inference]

ubiquitin-like protein-specific endopeptidase activity [inference]

SUMO-specific endopeptidase activity

cysteine-type peptidase activity [inference]

cysteine-type endopeptidase activity [inference]

ubiquitin-like protein-specific endopeptidase activity [inference]

SUMO-specific endopeptidase activity

ubiquitin-like protein peptidase activity [inference]

ubiquitin-like protein-specific endopeptidase activity [inference]

SUMO-specific endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

cysteine-type endopeptidase activity [inference]

ubiquitin-like protein-specific endopeptidase activity [inference]

SUMO-specific endopeptidase activity

cysteine-type peptidase activity [inference]

cysteine-type endopeptidase activity [inference]

ubiquitin-like protein-specific endopeptidase activity [inference]

SUMO-specific endopeptidase activity

ubiquitin-like protein peptidase activity [inference]

ubiquitin-like protein-specific endopeptidase activity [inference]

SUMO-specific endopeptidase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sentrin-specific protease 7

Functional Category

L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
SUMO-specific endopeptidase activity
hydrolase activity
proteolysis

Displaying **all 2** entries
InterPro
Papain-like cysteine peptidase superfamily
Ulp1 protease family, C-terminal catalytic domain

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Last updated: April 6, 2026

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