GlyCosmos Portal

Displaying **all 5** entries
GO Term	Evidence Code	PMID
mitochondrial inner membrane	IDA ISS TAS	9635427
mitochondrial permeability transition pore complex	IDA	26387735
mitochondrion	HTP	34800366
axon cytoplasm	IEA
m-AAA complex	IBA IDA	28396416

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

pore complex [inference]

mitochondrial permeability transition pore complex

inner mitochondrial membrane protein complex [inference]

m-AAA complex

mitochondrial protein-containing complex [inference]

mitochondrial permeability transition pore complex

inner mitochondrial membrane protein complex [inference]

m-AAA complex

catalytic complex [inference]

peptidase complex [inference]

m-AAA complex

cellular anatomical entity [inference]

cytoplasm [inference]

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

axon cytoplasm

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
ATP binding	IEA
ATP-dependent peptidase activity	IEA
unfolded protein binding	TAS	9635427

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

endopeptidase activity [inference]

metalloendopeptidase activity

ATP-dependent peptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a protein [inference]

peptidase activity

endopeptidase activity [inference]

metalloendopeptidase activity

ATP-dependent peptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

protein binding

unfolded protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATP-dependent peptidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATP-dependent zinc metalloprotease

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
hydrolase activity
metalloendopeptidase activity
metallopeptidase activity
proteolysis

Displaying **all 8** entries
InterPro
AAA ATPase, AAA+ lid domain
AAA+ ATPase domain
ATP-dependent zinc metalloprotease, FtsH
ATPase, AAA-type, conserved site
ATPase, AAA-type, core
P-loop containing nucleoside triphosphate hydrolase
Peptidase M41-like
Peptidase M41

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110816	hereditary spastic paraplegia 7	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	31253		FB:FBgn0024992
Caenorhabditis elegans	177021		WB:WBGene00021425
Caenorhabditis elegans	189973		WB:WBGene00021615
Mus musculus	234847		MGI:2385906	MOUSE59156
Rattus norvegicus	353231		RGD:727940	RATNO15102
Canis lupus familiaris	489657			CANLF15848
Bos taurus	515269			BOVIN10329
Macaca mulatta	699488			MACMU27377
Pan troglodytes	737127	9598_0:00407d
Danio rerio	794740		ZFIN:ZDB-GENE-030131-5391