GlyCosmos Portal

Displaying **all 5** entries
GO Term	Evidence Code	PMID
mitochondrial inner membrane	IDA ISS TAS	9635427
mitochondrial permeability transition pore complex	IDA	26387735
mitochondrion	HTP	34800366
axon cytoplasm	IEA
m-AAA complex	IBA IDA	28396416

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

pore complex [inference]

mitochondrial permeability transition pore complex

inner mitochondrial membrane protein complex [inference]

m-AAA complex

mitochondrial protein-containing complex [inference]

mitochondrial permeability transition pore complex

inner mitochondrial membrane protein complex [inference]

m-AAA complex

catalytic complex [inference]

peptidase complex [inference]

m-AAA complex

cellular anatomical entity [inference]

cytoplasm [inference]

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

axon cytoplasm

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	14623864 16189514 21516116 25416956 26387735 28514442 32296183 33961781
zinc ion binding	IEA
ATP hydrolysis activity	IEA
metalloendopeptidase activity	IBA IDA	28396416 31097542
peptidase activity	TAS	9635427

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

endopeptidase activity [inference]

metalloendopeptidase activity

ATP-dependent peptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a protein [inference]

peptidase activity

endopeptidase activity [inference]

metalloendopeptidase activity

ATP-dependent peptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

protein binding

unfolded protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATP-dependent peptidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATP-dependent zinc metalloprotease

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
hydrolase activity
metalloendopeptidase activity
metallopeptidase activity
proteolysis

Displaying **all 8** entries
InterPro
AAA ATPase, AAA+ lid domain
AAA+ ATPase domain
ATP-dependent zinc metalloprotease, FtsH
ATPase, AAA-type, conserved site
ATPase, AAA-type, core
P-loop containing nucleoside triphosphate hydrolase
Peptidase M41-like
Peptidase M41

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110816	hereditary spastic paraplegia 7	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 89 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Monodelphis domestica	100027002			MONDO09208
Equus caballus	100051955			HORSE30105
Oryctolagus cuniculus	100342856			RABIT17955
Callithrix jacchus	100407925			CALJA21689
Pongo abelii	100432082	9601_0:0040aa		PONAB10617
Ailuropoda melanoleuca	100466361			AILME04960
Xenopus tropicalis	100485977		Xenbase:XB-GENE-6034036
Nomascus leucogenys	100604082			NOMLE25740
Loxodonta africana	100672748			LOXAF06261
Oreochromis niloticus	100707281			ORENI34656