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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
steroid 5 alpha-reductase 1
Summary
- Gene Symbol
-
- SRD5A1
- Aliases
-
- 3-oxo-5-alpha-steroid 4-dehydrogenase 1
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to growth hormone | ||
| bone development | ||
| male gonad development | ||
| diterpenoid metabolic process | ||
| liver development |
GO Hierarchy
- response to xenobiotic stimulus
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
cellular response to chemical stimulus [inference]
response to nitrogen compound [inference]
cellular response to stimulus [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| neuronal cell body | ||
| endoplasmic reticulum membrane |
|
|
| perinuclear region of cytoplasm | ||
| cell body fiber |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| electron transfer activity |
|
|
| amide binding | ||
| NADPH binding | ||
| 3-oxo-5-alpha-steroid 4-dehydrogenase activity | ||
| 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050639 | primary cutaneous amyloidosis | |
| DOID:0050741 | alcohol dependence | |
| DOID:0050801 | androgenic alopecia | |
| DOID:0050830 | peripheral artery disease | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:10892 | hypospadias | |
| DOID:11132 | prostatic hypertrophy | |
| DOID:11432 | endometriosis of ovary |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002172
- Gene Name
- steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 184699 | WB:WBGene00008959 | ||
| 185670 | WB:WBGene00009635 | ||
| 100176622 | CIOIN04884 | ||
| 100186253 | CIOIN13332 | ||
| 103183194 | CALMI26772 | ||
| 102346093 | LATCH01596 | ||
| 767715 | ZFIN:ZDB-GENE-060929-938 | DANRE15790 | |
| 103038993 | ASTMX15808 | ||
| 113590333 | ELEEL44709 | ||
| 105012405 | ESOLU27192 |
