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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
steroid 5 alpha-reductase 1
Summary
- Gene Symbol
-
- SRD5A1
- Aliases
-
- 3-oxo-5-alpha-steroid 4-dehydrogenase 1
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to testosterone stimulus | ||
| cell differentiation | ||
| pituitary gland development | ||
| cellular response to estradiol stimulus |
GO Hierarchy
- response to xenobiotic stimulus
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
cellular response to chemical stimulus [inference]
response to nitrogen compound [inference]
cellular response to stimulus [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| neuronal cell body | ||
| endoplasmic reticulum membrane |
|
|
| perinuclear region of cytoplasm | ||
| cell body fiber |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| electron transfer activity |
|
|
| amide binding | ||
| NADPH binding | ||
| 3-oxo-5-alpha-steroid 4-dehydrogenase activity | ||
| 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3312 | bipolar disorder | |
| DOID:341 | peripheral vascular disease | |
| DOID:3459 | breast carcinoma | |
| DOID:3620 | central nervous system cancer | |
| DOID:3669 | intermittent claudication | |
| DOID:4766 | embryoma | |
| DOID:4964 | neurotic disorder | |
| DOID:5076 | mixed glioma | |
| DOID:591 | phobic disorder | |
| DOID:594 | panic disorder |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002172
- Gene Name
- steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115409658 | SALFA48376 | ||
| 109112475 | CYPCA108628 | ||
| 103735348 | NANGA10397 | ||
| 116448201 | CORMO09275 | ||
| 103257156 | CARSF19321 | ||
| 115617808 | STRHB14955 |
