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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
B-Raf proto-oncogene, serine/threonine kinase
Summary
- Gene Symbol
-
- BRAF
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Allosteric enzyme
- Cardiomyopathy
- Cell membrane
- Chromosomal rearrangement
- Cytoplasm
- Deafness
- Direct protein sequencing
- Disease variant
- Ectodermal dysplasia
- Intellectual disability
- Isopeptide bond
- Methylation
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Serine/threonine-protein kinase
- Ubl conjugation
- Zinc-finger
- Proteins
| UniProt | Protein Name |
|---|---|
| P15056 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to calcium ion | ||
| synaptic vesicle exocytosis | ||
| visual learning | ||
| negative regulation of apoptotic process | ||
| thyroid gland development |
GO Hierarchy
- regulation of cell population proliferation
biological process
metabolic process [inference]
cellular process [inference]
multicellular organismal process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| MAP kinase kinase kinase activity | ||
| small GTPase binding | ||
| scaffold protein binding | ||
| protein serine/threonine kinase activity | ||
| mitogen-activated protein kinase kinase binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050700 | cardiomyopathy | |
| DOID:0050861 | colorectal adenocarcinoma | |
| DOID:0060233 | cardiofaciocutaneous syndrome | |
| DOID:0060585 | Noonan syndrome 7 | |
| DOID:0080550 | Noonan syndrome with multiple lentigines 3 | |
| DOID:0111460 | cardiofaciocutaneous syndrome 1 | |
| DOID:1324 | lung cancer | |
| DOID:1520 | colon carcinoma | |
| DOID:162 | cancer | |
| DOID:1793 | pancreatic cancer |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 177436 | WB:WBGene00003030 | ||
| 31221 | FB:FBgn0003079 | ||
| 778741 | CIOIN16430 | ||
| 103181856 | CALMI23895 | ||
| 403065 | ZFIN:ZDB-GENE-040805-1 | DANRE32671 | |
| 113572532 | ELEEL12323 | ||
| 115183182 | SALTR50967 | ||
| 115183708 | SALTR50967 | ||
| 115541424 | GADMO47215 | ||
| 100708231 | ORENI24258 |
