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signal recognition particle 72

Summary

Gene Symbol

SRP72

Organism

Homo sapiens (human)

External Links

NCBI Gene

6731

PubChem

6731

Alliance of Genome Resources

HGNC:11303

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cytoplasm
Direct protein sequencing
Disease variant
Endoplasmic reticulum
Isopeptide bond
Phosphoprotein
Reference proteome
Repeat
Signal recognition particle
TPR repeat
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
V9HWK0
O76094	Signal recognition particle 72 kDa protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
SRP-dependent cotranslational protein targeting to membrane	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of localization [inference]

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER [inference]

SRP-dependent cotranslational protein targeting to membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane [inference]

cotranslational protein targeting to membrane [inference]

SRP-dependent cotranslational protein targeting to membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
signal recognition particle	IDA	27899666
endoplasmic reticulum	IDA	22541560
cytosol	TAS
signal recognition particle, endoplasmic reticulum targeting	IBA IDA	18089836

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex [inference]

signal recognition particle

signal recognition particle, endoplasmic reticulum targeting

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	16672232 24965446 32296183 33961781 35271311
TPR domain binding	IPI	27899666
ribosome binding	IBA IMP	27899666
signal recognition particle binding	IPI	17254600
RNA binding	HDA	22658674 22681889

GO Hierarchy

molecular function

binding [inference]

protein binding

protein domain specific binding [inference]

TPR domain binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

organic cyclic compound binding [inference]

nucleic acid binding [inference]

7S RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Signal recognition particle

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
7S RNA binding
SRP-dependent cotranslational protein targeting to membrane

Displaying **all 4** entries
InterPro
Signal recognition particle subunit SRP72, TPR-like repeat
Signal recognition particle, SRP72 subunit, RNA-binding
Signal recognition particle, SRP72 subunit
Tetratricopeptide-like helical domain superfamily

Ortholog

Displaying entries **1 - 10** of **100** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	42439		FB:FBgn0038810
Mus musculus	66661		MGI:1333795	MOUSE44476
Caenorhabditis elegans	173625		WB:WBGene00017245
Danio rerio	327335		ZFIN:ZDB-GENE-030131-5546
Canis lupus familiaris	403944			CANLF03411
Xenopus laevis	444393		Xenbase:XB-GENE-994744
Pan troglodytes	461308	9598_0:00157e
Xenopus tropicalis	496794		Xenbase:XB-GENE-994739
Rattus norvegicus	498351		RGD:1564787	RATNO07803
Bos taurus	509430			BOVIN31527

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Last updated: December 9, 2024