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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ST14 transmembrane serine protease matriptase
Summary
- Gene Symbol
-
- ST14
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Disease variant
- Disulfide bond
- Glycoprotein
- Hypotrichosis
- Ichthyosis
- Reference proteome
- Repeat
- Serine protease
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9Y5Y6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| epithelial cell morphogenesis involved in placental branching | ||
| protein catabolic process | ||
| keratinocyte differentiation | ||
| neural tube closure |
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| plasma membrane | ||
| basolateral plasma membrane | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type peptidase activity | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Serine protease
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060074 | ductal carcinoma in situ | |
| DOID:0060720 | autosomal recessive congenital ichthyosis 11 | |
| DOID:12894 | Sjogren's syndrome | |
| DOID:2999 | granulosa cell tumor | |
| DOID:4441 | dysgerminoma | |
| DOID:4450 | renal cell carcinoma | |
| DOID:8634 | prostate carcinoma in situ |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 19143 | MGI:1338881 | MOUSE60621 | ||
| 35904 | FB:FBgn0265011 | |||
| 41958 | FB:FBgn0003319 | |||
| 114093 | RGD:69288 | RATNO39873 | ||
| 246575 | FB:FBgn0050375 | |||
| 394363 | Xenbase:XB-GENE-1008789 | |||
| 448647 | Xenbase:XB-GENE-1008784 | |||
| 494753 | Xenbase:XB-GENE-6255322 | |||
| 557248 | ZFIN:ZDB-GENE-140106-74 | |||
| 678603 | ZFIN:ZDB-GENE-030131-6496 | DANRE13915 |
