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MIRAGE
signal transducer and activator of transcription 3
Summary
- Gene Symbol
-
- STAT3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Alternative splicing
- Coiled coil
- Cytoplasm
- DNA-binding
- Diabetes mellitus
- Disease variant
- Dwarfism
- Host-virus interaction
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- SH2 domain
- Transcription regulation
- Proteins
| UniProt | Protein Name |
|---|---|
| P40763 |
|
| A0A7I2V395 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| temperature homeostasis | ||
| eye photoreceptor cell differentiation | ||
| regulation of DNA-templated transcription | ||
| regulation of transcription, DNA-templated |
GO Hierarchy
- leptin-mediated signaling pathway
- interleukin-15-mediated signaling pathway
- interleukin-2-mediated signaling pathway
- interleukin-9-mediated signaling pathway
- interleukin-11-mediated signaling pathway
- interleukin-23-mediated signaling pathway
- interleukin-6-mediated signaling pathway
- interleukin-10-mediated signaling pathway
- intracellular receptor signaling pathway
- cell population proliferation
- leptin-mediated signaling pathway
- interleukin-15-mediated signaling pathway
- interleukin-2-mediated signaling pathway
- interleukin-9-mediated signaling pathway
- interleukin-11-mediated signaling pathway
- interleukin-23-mediated signaling pathway
- interleukin-6-mediated signaling pathway
- interleukin-10-mediated signaling pathway
- intracellular receptor signaling pathway
- regulation of cell cycle
- regulation of multicellular organism growth
biological process
metabolic process [inference]
cellular process [inference]
signal transduction
cell surface receptor signaling pathway [inference]
cytokine-mediated signaling pathway
cellular metabolic process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of transcription, DNA-templated
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of transcription, DNA-templated
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of nitrogen compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of transcription, DNA-templated
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction
cell surface receptor signaling pathway [inference]
cytokine-mediated signaling pathway
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of transcription, DNA-templated
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of molecular function [inference]
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Signal transducer and activator of transcription
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine-mediated signaling pathway |
| receptor signaling pathway via JAK-STAT |
| regulation of cell population proliferation |
| response to peptide hormone |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:234 | colon adenocarcinoma | |
| DOID:2394 | ovarian cancer | |
| DOID:3261 | hyper IgE recurrent infection syndrome 1 | |
| DOID:4450 | renal cell carcinoma | |
| DOID:5520 | head and neck squamous cell carcinoma | |
| DOID:7148 | rheumatoid arthritis | |
| DOID:8577 | ulcerative colitis | |
| DOID:8778 | Crohn's disease | |
| DOID:8893 | psoriasis | |
| DOID:9008 | psoriatic arthritis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101966508 | ICTTR18758 | ||
| 102016970 | CHILA12716 | ||
| 102186154 | CAPHI10936 | ||
| 102422489 | MYOLU07007 | ||
| 103033344 | ASTMX10187 | ||
| 103189176 | CALMI40848 | ||
| 103243410 | CHLSB05878 | ||
| 103672573 | URSMA31294 | ||
| 103735896 | NANGA15454 | ||
| 103821588 | SERCA18180 |
