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MIRAGE
stromal interaction molecule 1
Summary
- Gene Symbol
-
- STIM1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium transport
- Cell membrane
- Coiled coil
- Cytoskeleton
- Disease variant
- Endoplasmic reticulum
- Glycoprotein
- Metal-binding
- Microtubule
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Sarcoplasmic reticulum
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| E9PRZ7 |
|
| G0XQ39 |
|
| A0A8V8TMG1 |
|
| Q13586 |
|
| A0A8V8TNW0 |
|
| A0A8V8TMF0 |
|
| H0YDB2 |
|
| A0A8V8TP73 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| store-operated calcium entry | ||
| store-operated calcium entry | ||
| detection of calcium ion | ||
| intracellular calcium ion homeostasis | ||
| activation of store-operated calcium channel activity |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
positive regulation of transport [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum | ||
| endoplasmic reticulum | ||
| endoplasmic reticulum membrane | ||
| endoplasmic reticulum membrane | ||
| microtubule |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protease binding | ||
| calcium channel regulator activity | ||
| calcium channel regulator activity | ||
| calcium channel regulator activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- stromal interaction molecule
- Functional Category
-
- G: Carbohydrate transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060354 | Stormorken syndrome | |
| DOID:0080089 | tubular aggregate myopathy 1 | |
| DOID:0111970 | immunodeficiency 10 | |
| DOID:1324 | lung cancer | |
| DOID:9253 | gastrointestinal stromal tumor | |
| DOID:9256 | colorectal cancer |
