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STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)

Summary

Gene Symbol

Stt3b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

68292

KEGG Gene ID

mmu:68292

PubChem

68292

Alliance of Genome Resources

MGI:1915542

Annotation

Keyword

Acetylation
Direct protein sequencing
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Magnesium
Manganese
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0R4J0D3
Q3TDQ1	B6dom1 antigen Source of immunodominant MHC-associated peptides

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
response to unfolded protein	ISO ISS
protein N-linked glycosylation via asparagine	IBA ISO ISS
protein N-linked glycosylation	ISO NAS	31831667
co-translational protein modification	ISO ISS
post-translational protein modification	IBA ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

proteasomal protein catabolic process [inference]

ERAD pathway

cellular process [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

response to topologically incorrect protein [inference]

response to unfolded protein

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

ERAD pathway

response to topologically incorrect protein [inference]

response to unfolded protein

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein-containing complex	ISO	28246125
oligosaccharyltransferase I complex
endoplasmic reticulum membrane	NAS	31831667
endoplasmic reticulum	ISO
oligosaccharyltransferase complex	ISO ISS NAS	31831667

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

oligosaccharyltransferase complex

oligosaccharyltransferase I complex

endoplasmic reticulum protein-containing complex [inference]

oligosaccharyltransferase complex

oligosaccharyltransferase I complex

catalytic complex [inference]

transferase complex [inference]

oligosaccharyltransferase complex

oligosaccharyltransferase I complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
dolichyl-diphosphooligosaccharide-protein glycotransferase activity	IBA ISO ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

oligosaccharyl transferase activity [inference]

dolichyl-diphosphooligosaccharide-protein glycotransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

Functional Category

H: Coenzyme transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 6** entries
Gene Ontology
dolichyl-diphosphooligosaccharide-protein glycotransferase activity
metal ion binding
oligosaccharyl transferase activity
post-translational protein modification
protein N-linked glycosylation via asparagine
transferase activity

Displaying **all 3** entries
InterPro
Oligosaccharyl transferase STT3, N-terminal domain
Oligosaccharyl transferase, STT3 subunit
STT3/PglB/AglB, core domain

KEGG BRITE Database

Orthology

K07151

Name

dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]

References

12887896

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05976	2.4.99.18	G72079JG	G57930PW

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080572	congenital disorder of glycosylation Iw	Alliance of Genome Resources
DOID:0080573	congenital disorder of glycosylation Ix	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP004846
Gene Name: STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)

Ortholog

Displaying entries **31 - 40** of **121** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Ficedula albicollis	101810403		FICAL00626
Mesocricetus auratus	101841193	10036_0:005206
Macaca fascicularis	101864904		MACFA25878
Chrysemys picta bellii	101933162		CHRPI11091
Ictidomys tridecemlineatus	101958715	43179_0:0026ed
Microtus ochrogaster	101999310	79684_0:000d43
Chinchilla lanigera	102023832	34839_0:001b3a	CHILA08920
Capra hircus	102176834		CAPHI14211
Xiphophorus maculatus	102219972		XIPMA05417
Haplochromis burtoni	102294068		HAPBU12889

GlyTouCan

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements