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RAB14, member RAS oncogene family

Summary

Gene Symbol

Rab14

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

68365

PubChem

68365

Alliance of Genome Resources

MGI:1915615

Annotation

Keyword

Acetylation
Cytoplasmic vesicle
Direct protein sequencing
Endosome
GTP-binding
Golgi apparatus
Hydrolase
Membrane
Methylation
Prenylation
Protein transport
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q50HX4
Q91V41

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
phagolysosome assembly	IBA
intracellular protein transport	IBA
Golgi to endosome transport	IMP	21238925
Golgi to endosome transport	IBA
body fluid secretion	ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

vesicle-mediated transport [inference]

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport [inference]

Golgi to endosome transport

early endosome to Golgi transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

Golgi to endosome transport

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

localization within membrane [inference]

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

cellular macromolecule localization [inference]

protein localization [inference]

apical protein localization

establishment of protein localization [inference]

protein transport

intracellular protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization [inference]

phagolysosome assembly

vesicle organization [inference]

phagolysosome assembly

vesicle fusion [inference]

endosomal vesicle fusion

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

endosomal vesicle fusion

organelle assembly [inference]

phagolysosome assembly

phagosome maturation

cellular component assembly [inference]

organelle assembly [inference]

phagolysosome assembly

membrane organization [inference]

membrane fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

endosomal vesicle fusion

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

apical protein localization

establishment of protein localization [inference]

protein transport

intracellular protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport [inference]

Golgi to endosome transport

early endosome to Golgi transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

secretion [inference]

body fluid secretion

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

Golgi to endosome transport

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

organic substance transport [inference]

protein transport

intracellular protein transport

nitrogen compound transport [inference]

protein transport

intracellular protein transport

establishment of protein localization [inference]

protein transport

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

Golgi to endosome transport

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

endocytic recycling

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

Golgi to endosome transport

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

localization within membrane [inference]

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

cellular macromolecule localization [inference]

protein localization [inference]

apical protein localization

establishment of protein localization [inference]

protein transport

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

regulation of cellular localization [inference]

regulation of protein localization

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of biological quality [inference]

regulation of body fluid levels [inference]

body fluid secretion

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
Golgi membrane	IEA
lysosome	ISO
early endosome	ISO
early endosome	IBA
late endosome	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

endosome membrane [inference]

early endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

endosome membrane [inference]

early endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

nuclear outer membrane-endoplasmic reticulum membrane network

plasma membrane region [inference]

apical plasma membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

secretory granule [inference]

lamellar body [inference]

alveolar lamellar body

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum [inference]

rough endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

secretory granule [inference]

lamellar body [inference]

alveolar lamellar body

intracellular organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum [inference]

rough endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

secretory granule [inference]

lamellar body [inference]

alveolar lamellar body

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
GTPase activity	ISS
GTPase activity	ISO
GTPase activity	TAS
GTPase activity	IBA
protein binding	IPI	21238925

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

myosin binding [inference]

myosin V binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

GDP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

RAB

Functional Category

T: Signal transduction mechanisms
U: Intracellular trafficking, secretion, and vesicular transport

Displaying 1 entry
Gene Ontology
GTP binding

Displaying **all 3** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Small GTP-binding protein domain
Small GTPase

Ortholog

Displaying entries **1 - 10** of 95 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	51552	Xenbase:XB-GENE-479093	HUMAN98235
Xenopus tropicalis	68365	Xenbase:XB-GENE-479093
Rattus norvegicus	94197		RATNO28127
Danio rerio	393656		DANRE37569
Canis lupus familiaris	474818		CANLF02498
Bos taurus	539180		BOVIN35233
Sus scrofa	595112		PIGXX16064
Macaca mulatta	699837		MACMU12989
Pan troglodytes	744531		PANTR44718
Monodelphis domestica	100015716		MONDO03996