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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
mitogen-activated protein kinase kinase kinase 7
Summary
- Gene Symbol
-
- MAP3K7
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Apoptosis
- Cell membrane
- Cytoplasm
- Disease variant
- Host-virus interaction
- Isopeptide bond
- Magnesium
- Metal-binding
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Stress response
- Transcription regulation
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| O43318 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of vascular associated smooth muscle cell migration | ||
| cellular response to angiotensin | ||
| toll-like receptor 4 signaling pathway | ||
| anoikis | ||
| interleukin-17A-mediated signaling pathway |
GO Hierarchy
biological process
immune system process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
immune response-regulating signaling pathway [inference]
regulation of adaptive immune response [inference]
regulation of innate immune response [inference]
positive regulation of immune response [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
positive regulation of response to biotic stimulus [inference]
positive regulation of signal transduction [inference]
positive regulation of defense response [inference]
positive regulation of response to external stimulus [inference]
positive regulation of immune response [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
positive regulation of response to biotic stimulus [inference]
positive regulation of signal transduction [inference]
positive regulation of defense response [inference]
positive regulation of response to external stimulus [inference]
positive regulation of immune response [inference]
regulation of immune response [inference]
immune response-regulating signaling pathway [inference]
regulation of adaptive immune response [inference]
regulation of innate immune response [inference]
positive regulation of immune response [inference]
regulation of response to stress [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum membrane | ||
| plasma membrane | ||
| endosome membrane | ||
| ATAC complex | ||
| nucleus |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- kinase
- Functional Category
-
- K: Transcription
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| kinase activity |
| nucleotide binding |
| phosphorylation |
| InterPro |
|---|
| Protein kinase domain |
| Protein kinase-like domain superfamily |
| Serine-threonine/tyrosine-protein kinase, catalytic domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111785 | frontometaphyseal dysplasia | |
| DOID:0111787 | frontometaphyseal dysplasia 2 | |
| DOID:10283 | prostate cancer | |
| DOID:11520 | benign hypertensive renal disease | |
| DOID:11984 | hypertrophic cardiomyopathy | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:2349 | arteriosclerosis | |
| DOID:3393 | coronary artery disease | |
| DOID:384 | Wolff-Parkinson-White syndrome | |
| DOID:5844 | myocardial infarction |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 26409 | MGI:1346877 | MOUSE42368 | ||
| 39659 | FB:FBgn0026323 | |||
| 172842 | WB:WBGene00003396 | |||
| 190882 | WB:WBGene00013643 | |||
| 313121 | RGD:1309438 | RATNO32398 | ||
| 379399 | Xenbase:XB-GENE-17339869 | |||
| 399459 | Xenbase:XB-GENE-481534 | |||
| 462888 | 9598_0:001cf3 | PANTR38711 | ||
| 529146 | BOVIN35676 | |||
| 553788 | ZFIN:ZDB-GENE-041001-135 | DANRE18992 |
