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dynein axonemal intermediate chain 1

Summary

Gene Symbol

Dnai1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

68922

PubChem

68922

Alliance of Genome Resources

MGI:1916172

Annotation

Keyword

Cilium
Cytoskeleton
Dynein
Microtubule
Motor protein
Phosphoprotein
Reference proteome
Repeat
WD repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8C0M8	Axonemal dynein intermediate chain 1
A2ANP4	Axonemal dynein intermediate chain 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
cilium movement	ISO
cilium movement	IBA
epithelial cilium movement involved in extracellular fluid movement	IMP	20498047
determination of left/right symmetry	ISO
determination of left/right symmetry	IMP	25807483

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement

epithelial cilium movement involved in extracellular fluid movement

cilium movement involved in cell motility [inference]

flagellated sperm motility

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility [inference]

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly [inference]

outer dynein arm assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly [inference]

outer dynein arm assembly

reproductive process [inference]

sperm motility [inference]

flagellated sperm motility

multicellular organismal process [inference]

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

heart development

localization [inference]

establishment of localization [inference]

transport [inference]

extracellular transport [inference]

epithelial cilium movement involved in extracellular fluid movement

microtubule-based transport [inference]

epithelial cilium movement involved in extracellular fluid movement

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
cytoplasm	IDA	28057765
centrosome	IDA	28057765
microtubule	IEA
cilium	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex [inference]

axonemal dynein complex [inference]

outer dynein arm

catalytic complex [inference]

dynein complex [inference]

axonemal dynein complex [inference]

outer dynein arm

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

motile cilium [inference]

9+2 motile cilium

glial cell projection

organelle [inference]

membrane-bounded organelle [inference]

cilium

motile cilium [inference]

9+2 motile cilium

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	28057765 29916806
dynein light chain binding	IBA
dynein heavy chain binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dynein intermediate chain

Functional Category

G: Carbohydrate transport and metabolism
L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
dynein heavy chain binding
dynein light chain binding
outer dynein arm assembly

Displaying **all 3** entries
InterPro
WD40 repeat
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050144	Kartagener syndrome	Alliance of Genome Resources
DOID:0050545	visceral heterotaxy	Alliance of Genome Resources
DOID:0110594	primary ciliary dyskinesia 1	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements