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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
pitrilysin metallepetidase 1
Summary
- Gene Symbol
-
- Pitrm1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Disulfide bond
- Metal-binding
- Metalloprotease
- Mitochondrion
- Reference proteome
- Transit peptide
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8K411 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| protein processing |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrion | ||
| mitochondrial matrix |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| zinc ion binding | ||
| metalloendopeptidase activity | ||
| metallopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- presequence protease, mitochondrial
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| metalloendopeptidase activity |
| proteolysis |
| zinc ion binding |
| InterPro |
|---|
| Metalloenzyme, LuxS/M16 peptidase-like |
| Peptidase M16, C-terminal |
| Peptidase M16, N-terminal |
| Peptidase M16C associated |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050951 | hereditary ataxia | |
| DOID:0070411 | autosomal recessive spinocerebellar ataxia 30 | |
| DOID:10652 | Alzheimer's disease | |
| DOID:9277 | primary cerebellar degeneration |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 10531 | HGNC:17663 | HUMAN00061 | ||
| 35475 | FB:FBgn0033005 | |||
| 175914 | WB:WBGene00015481 | |||
| 307081 | 10116_1:004cac | RGD:1310998 | RATNO12740 | |
| 406808 | ZFIN:ZDB-GENE-040426-2876 | DANRE29031 | ||
| 450267 | PANTR00033 | |||
| 478018 | CANLF06599 | |||
| 513230 | BOVIN04665 | |||
| 710684 | MACMU44915 | |||
| 734137 | Xenbase:XB-GENE-952658 |
