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Standards Ontologies Notations
ST3 beta-galactoside alpha-2,3-sialyltransferase 1

Summary
Gene Symbol
  • ST3GAL1
Organism
Macaca mulatta (Rhesus monkey)
NCBI Gene
698004
KEGG Gene ID
mcc:698004
PubChem
698004
Annotation
Keyword
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Reference proteome
  • Secreted
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
A0A1D5RE99
  • Gal-NAc6S
  • Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase
  • Monosialoganglioside sialyltransferase
  • ST3Gal I
  • ST3GalA.1
  • ST3O
  • Sialyltransferase 4A
A0A8J8XDP6
  • Gal-NAc6S
  • Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase
  • Monosialoganglioside sialyltransferase
  • ST3Gal I
  • ST3GalA.1
  • ST3O
  • Sialyltransferase 4A
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
sialyltransferase activity
transferase activity
Displaying all 2 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
KEGG BRITE Database
Orthology
K00780
Name
beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.3.2 2.4.3.4]
References
Reactions
Displaying all 5 entries
KEGG Reaction Enzyme Acceptor Product
R05949
R05942
R05957
R05967
R05913
Rhea

RHEA:52380

a β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl derivative + H+ + CMP
Enzyme
PMID

RHEA:18021

CMP-N-acetyl-β-neuraminate + a ganglioside GM1 (d18:1(4E))
H+ + CMP + a ganglioside GD1a (d18:1(4E))
Enzyme
PMID

RHEA:21616

a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + H+ + CMP
Enzyme
PMID
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP014909
Gene Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Ortholog
Displaying entries 11 - 20 of 70 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
100438644 PONAB34876
100467054 AILME15985
100553436 ANOCA05282
100583104 NOMLE11460
100667581 LOXAF16560
100720961 CAVPO17263
100924982 SARHA14058
100966471 OTOGA09370
100987531 PANPA38924
101016088 9555_0:00234f PAPAN38259
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024