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oxoglutarate dehydrogenase

Summary

Gene Symbol

OGDH

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 698854
KEGG Gene ID: mcc:698854
PubChem: 698854

Annotation

Keyword

Calcium
Isopeptide bond
Nucleus
Oxidoreductase
Reference proteome
Thiamine pyrophosphate
Transit peptide
Ubl conjugation

Proteins

Displaying **all 5** entries
UniProt	Protein Name
A0A1D5QHY1	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
A0A1D5RCY7	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
A0A8J8XX26	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
F7H508	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
G7MLD3	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
tricarboxylic acid cycle	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

tricarboxylic acid cycle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxoglutarate dehydrogenase complex	IEA	30032202
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

tricarboxylic acid cycle enzyme complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

oxidoreductase complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

transferase complex [inference]

oxoglutarate dehydrogenase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxoglutarate dehydrogenase (succinyl-transferring) activity	IEA	22301074 30032202
thiamine pyrophosphate binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [inference]

oxoglutarate dehydrogenase (succinyl-transferring) activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

thiamine pyrophosphate binding

quaternary ammonium group binding [inference]

thiamine pyrophosphate binding

heterocyclic compound binding [inference]

thiamine pyrophosphate binding

ion binding [inference]

anion binding [inference]

thiamine pyrophosphate binding

cation binding [inference]

thiamine pyrophosphate binding

organic cyclic compound binding [inference]

thiamine pyrophosphate binding

sulfur compound binding [inference]

thiamine pyrophosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00164

Name

2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]

References

Rhea

RHEA:12188

H⁺ + 2-oxoglutarate

CO₂

Enzyme

1.2.4.2

PMID

Ortholog

Displaying entries **1 - 10** of **105** in total

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Species	Gene ID	Orthologous MAtrix
Callorhinchus milii	103187816	CALMI37595
Danio rerio	564552	DANRE43165
Danio rerio	797715	DANRE00348
Astyanax mexicanus	103040949	ASTMX05934
Ictalurus punctatus	108265558	ICTPU29174
Ictalurus punctatus	108277078	ICTPU09275
Electrophorus electricus	113583610	ELEEL05781
Electrophorus electricus	113590239	ELEEL44601
Esox lucius	105014042	ESOLU39315
Esox lucius	105015304	ESOLU40406

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UniCarb-DR

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Other Information

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements