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transmembrane BAX inhibitor motif containing 6

Summary

Gene Symbol

TMBIM6

Organism

Homo sapiens (human)

External Links

NCBI Gene

7009

PubChem

7009

Alliance of Genome Resources

HGNC:11723

JoGo

TMBIM6

TogoVar

TMBIM6

Annotation

Keyword

Alternative splicing
Apoptosis
Autophagy
Calcium
Endoplasmic reticulum
Isopeptide bond
Proteomics identification
Reference proteome
Transmembrane helix
Ubl conjugation
Unfolded protein response

Proteins

Displaying 1 entry
UniProt	Protein Name
P55061	Testis-enhanced gene transcript protein Transmembrane BAX inhibitor motif-containing protein 6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
negative regulation of immunoglobulin production	IEA
autophagy	IEA
negative regulation of calcium ion transport into cytosol	IDA	26582200
endoplasmic reticulum calcium ion homeostasis	IEA
negative regulation of RNA splicing	IDA	19328063

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [inference]

neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [inference]

neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [inference]

neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

process utilizing autophagic mechanism [inference]

autophagy

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [inference]

neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

response to topologically incorrect protein [inference]

response to unfolded protein [inference]

cellular response to unfolded protein

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

response to chemical [inference]

response to acid chemical [inference]

response to amino acid [inference]

response to L-glutamate

response to organic substance [inference]

response to organonitrogen compound [inference]

response to amino acid [inference]

response to L-glutamate

response to topologically incorrect protein [inference]

response to unfolded protein [inference]

cellular response to unfolded protein

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to amino acid [inference]

response to L-glutamate

response to oxygen-containing compound [inference]

response to amino acid [inference]

response to L-glutamate

response to salt [inference]

response to L-glutamate

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [inference]

neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to unfolded protein

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

negative regulation of immunoglobulin production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

negative regulation of immunoglobulin production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

regulation of RNA splicing [inference]

negative regulation of RNA splicing

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

negative regulation of RNA splicing

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

negative regulation of immunoglobulin production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

regulation of RNA splicing [inference]

negative regulation of RNA splicing

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

negative regulation of RNA splicing

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

negative regulation of immunoglobulin production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

regulation of RNA splicing [inference]

negative regulation of RNA splicing

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of nuclease activity [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

negative regulation of RNA splicing

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

negative regulation of RNA splicing

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of hypoxia-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of hypoxia-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of cellular localization [inference]

regulation of calcium ion transport into cytosol [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of cellular response to hypoxia [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of cellular response to hypoxia [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of hypoxia-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of hypoxia-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of cellular response to hypoxia [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of cellular response to hypoxia [inference]

negative regulation of cellular response to hypoxia [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [inference]

neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [inference]

neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of intracellular signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of hypoxia-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of hypoxia-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of RNA metabolic process [inference]

regulation of RNA splicing [inference]

negative regulation of RNA splicing

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

negative regulation of immunoglobulin production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

regulation of RNA splicing [inference]

negative regulation of RNA splicing

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of hypoxia-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of intracellular signal transduction [inference]

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of RNA splicing

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of RNA splicing

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of apoptotic signaling pathway

negative regulation of intrinsic apoptotic signaling pathway [inference]

negative regulation of cellular response to hypoxia [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of cellular localization [inference]

regulation of calcium ion transport into cytosol [inference]

negative regulation of calcium ion transport into cytosol

regulation of cellular response to stress [inference]

regulation of cellular response to hypoxia [inference]

negative regulation of cellular response to hypoxia [inference]

negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of IRE1-mediated unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [inference]

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of IRE1-mediated unfolded protein response

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

regulation of biological quality [inference]

regulation of calcium ion transport into cytosol [inference]

negative regulation of calcium ion transport into cytosol

negative regulation of cytosolic calcium ion concentration [inference]

negative regulation of calcium ion transport into cytosol

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of hydrolase activity [inference]

regulation of nuclease activity [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of hydrolase activity [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleus	TAS	8530040
cytoplasm	IDA	9660918
endoplasmic reticulum	IDA	19328063 21068390
endoplasmic reticulum membrane	IDA	25764978 9660918
endoplasmic reticulum membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
calcium channel activity	IBA
protein binding	IPI	28514442 30559186 32296183 33961781 9660918
enzyme binding	IPI	19328063
ubiquitin protein ligase binding	IPI	21068390
endoribonuclease inhibitor activity	IDA	19328063