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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
thyroglobulin
Summary
- Gene Symbol
-
- TG
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Congenital hypothyroidism
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Iodination
- Proteoglycan
- Reference proteome
- Repeat
- Secreted
- Signal
- Sulfation
- Thyroid hormone
- Thyroid hormones biosynthesis
- Proteins
| UniProt | Protein Name |
|---|---|
| P01266 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of myelination | ||
| thyroid gland development | ||
| iodide transport | ||
| hormone biosynthetic process | ||
| thyroid hormone generation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| identical protein binding | ||
| hormone activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- uncharacterized protein
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| thyroid hormone generation |
| InterPro |
|---|
| Thyroglobulin type-1 superfamily |
| Thyroglobulin type-1 |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0060870 | isolated growth hormone deficiency | |
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0112187 | thyroid dyshormonogenesis 3 | |
| DOID:12176 | goiter | |
| DOID:12361 | Graves' disease | |
| DOID:14018 | alcoholic liver cirrhosis | |
| DOID:1459 | hypothyroidism | |
| DOID:7188 | autoimmune thyroiditis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 21819 | MGI:98733 | MOUSE15521 | ||
| 24826 | RGD:3848 | RATNO39395 | ||
| 280706 | BOVIN05691 | |||
| 464407 | 9598_0:002728 | PANTR43293 | ||
| 482047 | CANLF03227 | |||
| 567631 | ZFIN:ZDB-GENE-030519-1 | DANRE11343 | ||
| 701756 | MACMU44618 | |||
| 100058029 | HORSE42794 | |||
| 100156471 | PIGXX22836 | |||
| 100379850 | Xenbase:XB-GENE-5870242 |
