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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
tight junction protein 1
Summary
- Gene Symbol
-
- TJP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calmodulin-binding
- Cell membrane
- Cell projection
- Gap junction
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- SH3 domain
- Tight junction
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell population proliferation | ||
| positive regulation of cell-cell adhesion mediated by cadherin | ||
| cell-cell adhesion | ||
| regulation of bicellular tight junction assembly | ||
| actomyosin structure organization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell junction | ||
| protein-containing complex | ||
| apical junction complex | ||
| plasma membrane | ||
| cell projection |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| calmodulin binding | ||
| cell adhesion molecule binding | ||
| cadherin binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- tight junction protein
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:13141 | uveitis | |
| DOID:13580 | cholestasis | |
| DOID:13976 | peptic esophagitis | |
| DOID:2316 | brain ischemia | |
| DOID:4606 | bile duct cancer | |
| DOID:4948 | gallbladder carcinoma | |
| DOID:8677 | perinatal necrotizing enterocolitis | |
| DOID:936 | brain disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 21872 | MGI:98759 | MOUSE51894 | ||
| 41062 | FB:FBgn0262614 | |||
| 173316 | WB:WBGene00013683 | |||
| 292994 | RGD:1306305 | RATNO17400 | ||
| 378845 | ZFIN:ZDB-GENE-031001-2 | DANRE40496 | ||
| 403752 | CANLF11995 | |||
| 443200 | SHEEP07802 | |||
| 453253 | 9598_0:003ce5 | PANTR09820 | ||
| 496307 | Xenbase:XB-GENE-17332215 | |||
| 565459 | ZFIN:ZDB-GENE-070925-1 | DANRE27132 |
