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6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

Summary

Gene Symbol

PFKFB4

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 709854
KEGG Gene ID: mcc:709854
PubChem: 709854

Annotation

Keyword

Kinase
Multifunctional enzyme
Nucleotide-binding
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A8J8XKK9
G7MIQ1
F6ZP74

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
fructose metabolic process	IEA	22301074
fructose 2,6-bisphosphate metabolic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

organophosphate metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

organophosphate metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

carbohydrate derivative metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

organophosphate metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
fructose-2,6-bisphosphate 2-phosphatase activity	IEA	30032202
ATP binding	IEA	22301074 30032202
6-phosphofructo-2-kinase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

carbohydrate kinase activity [inference]

phosphofructokinase activity [inference]

6-phosphofructo-2-kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

phosphofructokinase activity [inference]

6-phosphofructo-2-kinase activity

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

carbohydrate phosphatase activity [inference]

sugar-phosphatase activity [inference]

fructose-2,6-bisphosphate 2-phosphatase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K19030

Name

6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46]

References

16311927

Ortholog

Displaying entries **71 - 80** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Equus asinus asinus	106830661		EQUAS00638
Chelonoidis abingdonii	116820429		CHEAB22859
Echeneis naucrates	115043356		ECHNA04635
Salarias fasciatus	115388804		SALFA37424
Athene cunicularia	113484722		ATHCN12966
Propithecus coquereli	105809144		PROCO00217
Cyprinus carpio carpio	109092986		CYPCA120165
Nannospalax galili	103750221		NANGA14074
Corvus moneduloides	116449191		CORMO01559
Carlito syrichta	103260622		CARSF19613

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: August 19, 2024