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phosphatidylserine decarboxylase

Summary

Gene Symbol

PISD

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 716905
KEGG Gene ID: mcc:716905
PubChem: 716905

Annotation

Keyword

Decarboxylase
Lipid droplet
Mitochondrion inner membrane
Phospholipid biosynthesis
Pyruvate
Reference proteome
Transmembrane helix
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
F6QD04

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
phosphatidylethanolamine biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrion	IEA	22301074 30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying 1 entry
GO Term	Evidence Code	PMID
phosphatidylserine decarboxylase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity [inference]

phosphatidylserine decarboxylase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phosphatidylserine decarboxylase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
carboxy-lyase activity
lipid metabolic process
lyase activity
phosphatidylethanolamine biosynthetic process
phosphatidylserine decarboxylase activity
phospholipid biosynthetic process
protein autoprocessing

Displaying **all 3** entries
InterPro
Phosphatidylserine decarboxylase, bacterial/eukaryotic
Phosphatidylserine decarboxylase, eukaryotic type 1
Phosphatidylserine decarboxylase-related

KEGG BRITE Database

Orthology

K01613

Name

phosphatidylserine decarboxylase [EC:4.1.1.65]

References

Rhea

H⁺ + a 1,2-diacyl-sn-glycero-3-phospho-L-serine

CO₂ + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine

Enzyme

4.1.1.65

PMID

Ortholog

Displaying entries **41 - 50** of 92 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Carlito syrichta	103263877			CARSF10539
Poecilia reticulata	103460430			POERE00696
Nannospalax galili	103740422			NANGA11285
Serinus canaria	103818023			SERCA12760
Rhinopithecus roxellana	104660359	61622_0:003459		RHIRO28712
Esox lucius	105015134			ESOLU43207
Macaca nemestrina	105487200	9545_0:000eae		MACNE40978
Colobus angolensis palliatus	105509186	336983_0:0011aa		COLAP36254
Mandrillus leucophaeus	105538957	9568_0:001732		MANLE01525
Cercocebus atys	105575752	9531_0:003591		CERAT19125

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024