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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
complement C1s
Summary
- Gene Symbol
-
- C1S
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Complement pathway
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Ehlers-Danlos syndrome
- Glycoprotein
- Hydroxylation
- Innate immunity
- Metal-binding
- Proteomics identification
- Reference proteome
- Repeat
- Serine protease
- Signal
- Sushi
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| innate immune response | ||
| complement activation, classical pathway | ||
| complement activation |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| blood microparticle | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| metal ion binding |
|
|
| identical protein binding | ||
| calcium ion binding | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Mannan-binding lectin serine protease 1
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Sushi/SCR/CCP domain |
| Sushi/SCR/CCP superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080987 | Ehlers-Danlos syndrome periodontal type 2 |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100558615 | ANOCA17150 | |||
| 100722315 | CAVPO22252 | |||
| 100917190 | SARHA04982 | |||
| 100952754 | OTOGA06391 | |||
| 100991971 | 9597_0:0034fd | PANPA08585 | ||
| 101034947 | SAIBB40393 | |||
| 101088676 | FELCA15725 | |||
| 101107688 | SHEEP14975 | |||
| 101145266 | 9595_0:0038da | GORGO06751 | ||
| 101324686 | TURTR10137 |
